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5L81
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Crystal structure of the PH domain of murine kindlin-3
分子名称: Fermitin family homolog 3, SODIUM ION
著者Ni, T, Harlos, K, Gilbert, R.J.C.
登録日2016-06-06
公開日2017-01-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structure and lipid-binding properties of the kindlin-3 pleckstrin homology domain.
Biochem. J., 474, 2017
5D68
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Crystal structure of KRIT1 ARD-FERM
分子名称: Krev interaction trapped protein 1
著者Zhang, R, Li, X, Boggon, T.J.
登録日2015-08-11
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.908 Å)
主引用文献Structural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD-FERM interface.
J.Struct.Biol., 192, 2015
4ZRK
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Merlin-FERM and Lats1 complex
分子名称: Merlin, Serine/threonine-protein kinase LATS1
著者Lin, Z, Li, Y, Wei, Z, Zhang, M.
登録日2015-05-12
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.316 Å)
主引用文献Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
Cell Res., 25, 2015
4ZRI
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Crystal structure of Merlin-FERM and Lats2
分子名称: Merlin, Serine/threonine-protein kinase LATS2
著者Li, F, Zhou, H, Long, J, Shen, Y.
登録日2015-05-12
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
Cell Res., 25, 2015
4ZRJ
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Structure of Merlin-FERM and CTD
分子名称: GLYCEROL, Merlin
著者Lin, Z, Li, F, Long, J, Shen, Y.
登録日2015-05-12
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
Cell Res., 25, 2015
4YL8
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Crystal structure of the Crumbs/Moesin complex
分子名称: GLYCEROL, IODIDE ION, Moesin, ...
著者Wei, Z, Li, Y, Zhang, M.
登録日2015-03-05
公開日2015-04-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Basis for the Phosphorylation-regulated Interaction between the Cytoplasmic Tail of Cell Polarity Protein Crumbs and the Actin-binding Protein Moesin
J.Biol.Chem., 290, 2015
3X23
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Radixin complex
分子名称: Peptide from Matrix metalloproteinase-14, Radixin
著者Terawaki, S, Kitano, K, Aoyama, M, Mori, T, Hakoshima, T.
登録日2014-12-09
公開日2015-10-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.396 Å)
主引用文献MT1-MMP recognition by ERM proteins and its implication in CD44 shedding
Genes Cells, 20, 2015
4RMA
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Crystal structure of the FERM domain of human ezrin
分子名称: Ezrin, SULFATE ION
著者Phang, J.M, Harrop, S.J, Duff, A.P, Wilk, K.E, Curmi, P.M.G.
登録日2014-10-21
公開日2015-12-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin.
Biochem. J., 473, 2016
4RM9
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Crystal structure of human ezrin in space group C2221
分子名称: Ezrin
著者Phang, J.M, Harrop, S.J, Davies, R, Duff, A.P, Wilk, K.E, Curmi, P.M.G.
登録日2014-10-21
公開日2015-12-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin.
Biochem. J., 473, 2016
4RM8
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Crystal structure of human ezrin in space group P21
分子名称: Ezrin
著者Phang, J.M, Harrop, S.J, Davies, R, Duff, A.P, Wilk, K.E, Curmi, P.M.G.
登録日2014-10-20
公開日2015-12-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin.
Biochem. J., 473, 2016
4CYE
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Crystal structure of avian FAK FERM domain FAK31-405 at 3.2A
分子名称: FOCAL ADHESION KINASE 1
著者Goni, G.M, Epifano, C, Boskovic, J, Camacho-Artacho, M, Zhou, J, Martin, M.T, Eck, M.J, Kremer, L, Graeter, F, Gervasio, F.L, Perez-Moreno, M, Lietha, D.
登録日2014-04-10
公開日2014-04-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes.
Proc.Natl.Acad.Sci.USA, 111, 2014
4P7I
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Crystal structure of the Merlin FERM/DCAF1 complex
分子名称: GLYCEROL, Merlin, Protein VPRBP
著者Wei, Z, Li, Y, Zhang, M.
登録日2014-03-27
公開日2014-04-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of the binding of Merlin FERM domain to the E3 ubiquitin ligase substrate adaptor DCAF1.
J.Biol.Chem., 289, 2014
4NY0
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Crystal structure of FERM domain of human focal adhesion kinase
分子名称: Focal adhesion kinase 1
著者Walkiewicz, K, Arold, S.T.
登録日2013-12-10
公開日2014-03-12
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献FAK dimerization controls its kinase-dependent functions at focal adhesions.
Embo J., 33, 2014
3WA0
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Crystal structure of merlin complexed with DCAF1/VprBP
分子名称: Merlin, Protein VPRBP
著者Mori, T, Gotoh, S, Shirakawa, M, Hakoshima, T.
登録日2013-04-20
公開日2014-05-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 function.
Genes Cells, 19, 2014
3ZDT
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Crystal structure of basic patch mutant FAK FERM domain FAK31- 405 K216A, K218A, R221A, K222A
分子名称: FOCAL ADHESION KINASE 1
著者Goni, G.M, Epifano, C, Boskovic, J, Camacho-Artacho, M, Zhou, J, Martin, M.T, Eck, M.J, Kremer, L, Graeter, F, Gervasio, F.L, Perez-Moreno, M, Lietha, D.
登録日2012-11-30
公開日2012-12-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes.
Proc.Natl.Acad.Sci.USA, 111, 2014
4HDQ
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Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and the Heart of Glass (HEG1) cytoplasmic tail
分子名称: GLYCEROL, Krev interaction trapped protein 1, MAGNESIUM ION, ...
著者Gingras, A.R.
登録日2012-10-02
公開日2013-07-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail.
J.Biol.Chem., 288, 2013
4HDO
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BU of 4hdo by Molmil
Crystal structure of the binary Complex of KRIT1 bound to the Rap1 GTPase
分子名称: GLYCEROL, Krev interaction trapped protein 1, MAGNESIUM ION, ...
著者Gingras, A.R.
登録日2012-10-02
公開日2013-07-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail.
J.Biol.Chem., 288, 2013
4BBK
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Structural and functional characterisation of the kindlin-1 pleckstrin homology domain
分子名称: FERMITIN FAMILY HOMOLOG 1, GLYCEROL
著者Yates, L.A, Lumb, C.N, Brahme, N.N, Zalyte, R, Bird, L.E, De Colibus, L, Owens, R.J, Calderwood, D.A, Sansom, M.S.P, Gilbert, R.J.C.
登録日2012-09-25
公開日2012-11-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Functional Characterisation of the Kindlin-1 Pleckstrin Homology Domain
J.Biol.Chem., 287, 2012
4F7G
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Crystal structure of talin autoinhibition complex
分子名称: Talin-1
著者Song, X, Qin, J, Ye, S, Zhang, R.
登録日2012-05-16
公開日2012-07-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.
Cell Res., 22, 2012
4F7H
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The crystal structure of kindlin-2 pleckstrin homology domain in free form
分子名称: Fermitin family homolog 2, S,R MESO-TARTARIC ACID
著者Liu, Y, Zhu, Y, Qin, J, Ye, S, Zhang, R.
登録日2012-05-16
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation.
Protein Cell, 3, 2012
4EKU
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Crystal Structure of FERM Domain of Proline-rich Tyrosine Kinase 2
分子名称: Protein-tyrosine kinase 2-beta
著者Savarimuthu, B, Li, R, Wang, Y.
登録日2012-04-09
公開日2012-04-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Crystal Structure of the Ferm Domain of Proline-rich Tyrosine Kinase 2
To be Published
4DXA
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Co-crystal structure of Rap1 in complex with KRIT1
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Krev interaction trapped protein 1, MAGNESIUM ION, ...
著者Li, X, Zhang, R, Boggon, T.J.
登録日2012-02-27
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1).
J.Biol.Chem., 287, 2012
2LKO
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Structural Basis of Phosphoinositide Binding to Kindlin-2 Pleckstrin Homology Domain in Regulating Integrin Activation
分子名称: Fermitin family homolog 2, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE
著者Liu, J, Fukuda, K, Xu, Z.
登録日2011-10-17
公開日2011-10-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation.
J.Biol.Chem., 286, 2011
3U8Z
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human merlin FERM domain
分子名称: Merlin
著者Yogesha, S.D, Sharff, A.J, Giovannini, M, Bricogne, G, Izard, T.
登録日2011-10-17
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Unfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressor.
Protein Sci., 20, 2011
3U7D
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Crystal structure of the KRIT1/CCM1 FERM domain in complex with the heart of glass (HEG1) cytoplasmic tail
分子名称: Krev interaction trapped protein 1, Protein HEG homolog 1
著者Gingras, A.R, Liu, J.J, Ginsberg, M.H, Assembly, Dynamics and Evolution of Cell-Cell and Cell-Matrix Adhesions (CELLMAT)
登録日2011-10-13
公開日2012-09-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural basis of the junctional anchorage of the cerebral cavernous malformations complex.
J.Cell Biol., 199, 2012

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