Crystal structure of KRIT1 ARD-FERM

Summary for 5D68

DescriptorKrev interaction trapped protein 1 (2 entities in total)
Functional Keywordsankyrin repeat domain, ferm domain, cerebral cavernous malformations, signaling protein
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm, cytoskeleton O00522
Total number of polymer chains3
Total molecular weight168462.5
Zhang, R.,Li, X.,Boggon, T.J. (deposition date: 2015-08-11, release date: 2015-10-21, Last modification date: 2017-09-13)
Primary citation
Zhang, R.,Li, X.,Boggon, T.J.
Structural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD-FERM interface.
J.Struct.Biol., 192:449-456, 2015
PubMed: 26458359 (PDB entries with the same primary citation)
DOI: 10.1016/j.jsb.2015.10.006
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.246301.5%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution