4RMA

Crystal structure of the FERM domain of human ezrin

Summary for 4RMA

Related4RM8 4RM9
DescriptorEzrin, SULFATE ION (3 entities in total)
Functional Keywordserm, ezrin, ferm domain, membrane cytoskeleton linkers, peptide binding protein
Biological sourceHomo sapiens (human)
Cellular locationApical cell membrane ; Peripheral membrane protein ; Cytoplasmic side  P15311
Total number of polymer chains2
Total molecular weight70349.21
Authors
Phang, J.M.,Harrop, S.J.,Duff, A.P.,Wilk, K.E.,Curmi, P.M.G. (deposition date: 2014-10-21, release date: 2015-12-09, Last modification date: 2017-09-27)
Primary citation
Phang, J.M.,Harrop, S.J.,Duff, A.P.,Sokolova, A.V.,Crossett, B.,Walsh, J.C.,Beckham, S.A.,Nguyen, C.D.,Davies, R.B.,Glockner, C.,Bromley, E.H.,Wilk, K.E.,Curmi, P.M.
Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin.
Biochem. J., 473:2763-2782, 2016
PubMed: 27364155 (PDB entries with the same primary citation)
DOI: 10.1042/BCJ20160541
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24440.2%1.7%7.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4rma
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Molmil generated image of 4rma
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Molmil generated image of 4rma
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More Biological unit images

Molmil generated image of 4rma
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Molmil generated image of 4rma
rotated about x axis by 90°
Molmil generated image of 4rma
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (4rma.pdb1.gz [111 KB])
Coordinate files for Biological unit (4rma.pdb2.gz [106.39 KB])
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