4NY0

Crystal structure of FERM domain of human focal adhesion kinase

Summary for 4NY0

Entry DOI	10.2210/pdb4ny0/pdb
Descriptor	Focal adhesion kinase 1 (1 entity in total)
Functional Keywords	ferm domain, focal adhesion kinase, focal targeting domain, integrin signaling, transferase
Biological source	Homo sapiens (human)
Cellular location	Cell junction, focal adhesion: Q05397
Total number of polymer chains	4
Total formula weight	172508.31
Authors	Walkiewicz, K.,Arold, S.T. (deposition date: 2013-12-10, release date: 2014-03-12, Last modification date: 2024-03-20)
Primary citation	Brami-Cherrier, K.,Gervasi, N.,Arsenieva, D.,Walkiewicz, K.,Boutterin, M.C.,Ortega, A.,Leonard, P.G.,Seantier, B.,Gasmi, L.,Bouceba, T.,Kadare, G.,Girault, J.A.,Arold, S.T. FAK dimerization controls its kinase-dependent functions at focal adhesions. Embo J., 33:356-370, 2014 Cited by PubMed: 24480479 DOI: 10.1002/embj.201386399 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation