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4NY0

Crystal structure of FERM domain of human focal adhesion kinase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(D, A, B, C)
Focal adhesion kinase 1polymer37643127.14UniProt (Q05397)
Pfam (PF18038)
Pfam (PF00373)
Pfam (PF21477)
Homo sapiens (human)FADK 1, Focal adhesion kinase-related nonkinase, FRNK, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK, pp125FAK
Sequence modifications
D, A, B, C: 31 - 405 (UniProt: Q05397)
PDBExternal DatabaseDetails
Met 30-expression tag
Leu 85Phe 85engineered mutation
Gly 181Trp 181engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight172508.3
All*Total formula weight172508.3
*Water molecules are not included.

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PDB entries from 2024-11-13

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