2LKO
Structural Basis of Phosphoinositide Binding to Kindlin-2 Pleckstrin Homology Domain in Regulating Integrin Activation
Summary for 2LKO
Entry DOI | 10.2210/pdb2lko/pdb |
NMR Information | BMRB: 18002 |
Descriptor | Fermitin family homolog 2, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE (2 entities in total) |
Functional Keywords | cell adhesion |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cell cortex: Q96AC1 |
Total number of polymer chains | 1 |
Total formula weight | 16222.23 |
Authors | Liu, J.,Fukuda, K.,Xu, Z. (deposition date: 2011-10-17, release date: 2011-10-26, Last modification date: 2024-05-15) |
Primary citation | Liu, J.,Fukuda, K.,Xu, Z.,Ma, Y.Q.,Hirbawi, J.,Mao, X.,Wu, C.,Plow, E.F.,Qin, J. Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation. J.Biol.Chem., 286:43334-43342, 2011 Cited by PubMed: 22030399DOI: 10.1074/jbc.M111.295352 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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