2LKO
Structural Basis of Phosphoinositide Binding to Kindlin-2 Pleckstrin Homology Domain in Regulating Integrin Activation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Fermitin family homolog 2 | polymer | 138 | 15722.2 | 1 | UniProt (Q96AC1) Pfam (PF00373) Pfam (PF00169) | Homo sapiens (human) | Kindlin-2, Mitogen-inducible gene 2 protein, MIG-2, Pleckstrin homology domain-containing family C member 1, PH domain-containing family C member 1 |
| 2 | B (A) | INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE | non-polymer | 500.1 | 1 | Chemie (4IP) |
Sequence modifications
A: 367 - 500 (UniProt: Q96AC1)
| PDB | External Database | Details |
|---|---|---|
| Gly 363 | - | expression tag |
| Ser 364 | - | expression tag |
| His 365 | - | expression tag |
| Met 366 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15722.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 500.1 | |
| All* | Total formula weight | 16222.2 |
