3WA0

Crystal structure of merlin complexed with DCAF1/VprBP

Summary for 3WA0

• Entry DOI: 10.2210/pdb3wa0/pdb
• Related: 1ISN 1J19 2YVC 2ZPY
• Descriptor: Merlin, Protein VPRBP, ... (6 entities in total)
• Functional Keywords: merlin ferm domain, cell adhesion
• Biological source: Mus musculus (mouse); More
• Cellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): P46662; Cytoplasm: Q9Y4B6
• Total number of polymer chains: 11
• Total formula weight: 235921.62

Authors

Mori, T.,Gotoh, S.,Shirakawa, M.,Hakoshima, T. (deposition date: 2013-04-20, release date: 2014-05-28, Last modification date: 2023-11-08)

• Primary citation: Mori, T.,Gotoh, S.,Shirakawa, M.,Hakoshima, T.; Structural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 function.; Genes Cells, 19:603-619, 2014; PubMed: 24912773; DOI: 10.1111/gtc.12161

Experimental method

X-RAY DIFFRACTION (2.31 Å)