3WA0
Crystal structure of merlin complexed with DCAF1/VprBP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Merlin | polymer | 301 | 35518.0 | 6 | UniProt (P46662) Pfam (PF09379) Pfam (PF00373) Pfam (PF09380) | Mus musculus (mouse) | Moesin-ezrin-radixin-like protein, Neurofibromin-2, Schwannomin |
| 2 | G, H (G, H) | Protein VPRBP | polymer | 96 | 10486.2 | 2 | UniProt (Q9Y4B6) | Homo sapiens (human) | DDB1- and CUL4-associated factor 1, HIV-1 Vpr-binding protein, VprBP, Vpr-interacting protein |
| 3 | I (I) | Protein VPRBP | polymer | 7 | 613.7 | 1 | Homo sapiens (human) | ||
| 4 | J (J) | Protein VPRBP | polymer | 8 | 698.9 | 1 | Homo sapiens (human) | ||
| 5 | K (K) | Protein VPRBP | polymer | 6 | 528.6 | 1 | Homo sapiens (human) | ||
| 6 | L, M, N, O, P... (A, B, C, D, E...) | water | water | 18.0 | 543 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 19 - 314 (UniProt: P46662)
G, H: 1417 - 1506 (UniProt: Q9Y4B6)
| PDB | External Database | Details |
|---|---|---|
| Gly 14 | - | expression tag |
| Pro 15 | - | expression tag |
| Leu 16 | - | expression tag |
| Gly 17 | - | expression tag |
| Ser 18 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 1411 | - | expression tag |
| Pro 1412 | - | expression tag |
| Leu 1413 | - | expression tag |
| Gly 1414 | - | expression tag |
| Ser 1415 | - | expression tag |
| Tyr 1416 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 235921.6 | |
| All* | Total formula weight | 235921.6 |
