2ZPY

Crystal structure of the mouse radxin FERM domain complexed with the mouse CD44 cytoplasmic peptide

Summary for 2ZPY

Entry DOI	10.2210/pdb2zpy/pdb
Related	1GC6 1GC7 1ISN 1J19 2D10 2D11 2D2Q 2EMS 2EMT 2YVC
Descriptor	Radixin, CD44 antigen (3 entities in total)
Functional Keywords	ferm domain, cd44, actin capping, actin-binding, cell membrane, cytoplasm, cytoskeleton, membrane, phosphoprotein, structural protein, alternative splicing, cell adhesion, glycoprotein, proteoglycan, pyrrolidone carboxylic acid, receptor, sulfation, transmembrane
Biological source	Mus musculus (mouse) More
Cellular location	Cell membrane; Peripheral membrane protein; Cytoplasmic side: P26043 Membrane; Single-pass type I membrane protein: P15379
Total number of polymer chains	2
Total formula weight	39112.18
Authors	Mori, T.,Kitano, K.,Terawaki, S.,Maesaki, R.,Fukami, Y.,Hakoshima, T. (deposition date: 2008-07-31, release date: 2008-08-26, Last modification date: 2023-11-01)
Primary citation	Mori, T.,Kitano, K.,Terawaki, S.,Maesaki, R.,Fukami, Y.,Hakoshima, T. Structural basis for CD44 recognition by ERM proteins J.Biol.Chem., 283:29602-29612, 2008 Cited by PubMed: 18753140 DOI: 10.1074/jbc.M803606200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation