PDB: 19326 件ウェブページステータス検索Chemie searchBIRD

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3MPH	The structure of human diamine oxidase complexed with an inhibitor aminoguanidine 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Amiloride-sensitive amine oxidase, CALCIUM ION, ... 著者 McGrath, A.P, Guss, J.M. 登録日 2010-04-27 公開日 2010-09-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Correlation of active site metal content in human diamine oxidase with trihydroxyphenylalanine quinone cofactor biogenesis Biochemistry, 49, 2010
3M3N	Structure of a Longitudinal Actin Dimer Assembled by Tandem W Domains 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Rebowski, G, Namgoong, S, Dominguez, R. 登録日 2010-03-09 公開日 2010-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (7 Å) 主引用文献 Structure of a longitudinal actin dimer assembled by tandem w domains: implications for actin filament nucleation. J.Mol.Biol., 403, 2010
3E5U	OCPA complexed CprK (C200S) 分子名称: (3-CHLORO-4-HYDROXYPHENYL)ACETIC ACID, Cyclic nucleotide-binding protein, PHOSPHATE ION, ... 著者 Levy, C. 登録日 2008-08-14 公開日 2008-09-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator Mol.Microbiol., 70, 2008
3N2K	TUBULIN-NSC 613862: RB3 Stathmin-like domain complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M. 登録日 2010-05-18 公開日 2010-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers. J.Biol.Chem., 285, 2010
3MVI	Crystal structure of holo mADA at 1.6 A resolution 分子名称: Adenosine deaminase, GLYCEROL, ZINC ION 著者 Niu, W, Shu, Q, Chen, Z, Mathews, S, Di Cera, E, Frieden, C. 登録日 2010-05-04 公開日 2010-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The role of Zn2+ on the structure and stability of murine adenosine deaminase. J.Phys.Chem.B, 114, 2010
3CIP	Complex of Dictyostelium Discoideum Actin with Gelsolin 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, GLYCEROL, ... 著者 Baek, K, Dominguez, R. 登録日 2008-03-11 公開日 2008-08-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Modulation of actin structure and function by phosphorylation of Tyr-53 and profilin binding. Proc.Natl.Acad.Sci.Usa, 105, 2008
3CJG	Crystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidine 分子名称: N~4~-methyl-N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine, SULFATE ION, Vascular endothelial growth factor receptor 2 著者 Nolte, R.T. 登録日 2008-03-12 公開日 2008-10-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor. J.Med.Chem., 51, 2008
3D0Q	Crystal structure of calG3 from Micromonospora echinospora determined in space group I222 分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Protein CalG3 著者 Bitto, E, Singh, S, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N. 登録日 2008-05-02 公開日 2008-06-24 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis. Chem.Biol., 15, 2008
8AVO	Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (open 3:3 model). 分子名称: Leptin, Leptin receptor 著者 Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. 登録日 2022-08-26 公開日 2023-04-05 最終更新日 2023-04-26 実験手法 ELECTRON MICROSCOPY (6.84 Å) 主引用文献 Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
8AVC	Mouse leptin:LEP-R complex cryoEM structure (3:3 model) 分子名称: Leptin, Leptin receptor, NICKEL (II) ION 著者 Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. 登録日 2022-08-26 公開日 2023-04-05 最終更新日 2023-04-26 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
8AVF	Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (closed 3:3 model) 分子名称: Leptin, Leptin receptor 著者 Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. 登録日 2022-08-26 公開日 2023-04-05 最終更新日 2023-04-26 実験手法 ELECTRON MICROSCOPY (6.45 Å) 主引用文献 Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
3MJ8	Crystal structure of HL4E10 Fab, a hamster Ab stimulatory for gammadelta T cells 分子名称: STIMULATORY HAMSTER ANTIBODY HL4E10 FAB HEAVY CHAIN, STIMULATORY HAMSTER ANTIBODY HL4E10 FAB LIGHT CHAIN 著者 Verdino, P, Wilson, I.A. 登録日 2010-04-12 公開日 2011-04-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 cDNA sequence and Fab crystal structure of HL4E10, a hamster IgG lambda light chain antibody stimulatory for gammadelta T cells. Plos One, 6, 2011
3CY6	Crystal Structure of E18Q DJ-1 分子名称: Protein DJ-1 著者 Witt, A.C, Lakshminarasimhan, M, Remington, B.C, Hasim, S, Pozharski, E, Wilson, M.A. 登録日 2008-04-25 公開日 2008-07-01 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Cysteine pKa depression by a protonated glutamic acid in human DJ-1. Biochemistry, 47, 2008
8AVE	Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (2:2 model) 分子名称: Leptin, Leptin receptor 著者 Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. 登録日 2022-08-26 公開日 2023-04-05 最終更新日 2023-04-26 実験手法 ELECTRON MICROSCOPY (5.62 Å) 主引用文献 Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
3N2O	X-ray crystal structure of arginine decarboxylase complexed with Arginine from Vibrio vulnificus 分子名称: AGMATINE, Biosynthetic arginine decarboxylase, PYRIDOXAL-5'-PHOSPHATE 著者 Deng, X, Lee, J, Michael, A.J, Tomchick, D.R, Goldsmith, E.J, Phillips, M.A. 登録日 2010-05-18 公開日 2010-06-09 最終更新日 2012-02-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Evolution of substrate specificity within a diverse family of beta/alpha-barrel-fold basic amino acid decarboxylases: X-ray structure determination of enzymes with specificity for L-arginine and carboxynorspermidine. J.Biol.Chem., 285, 2010
3E5C	Crystal Structure of the SMK box (SAM-III) Riboswitch with SAM 分子名称: S-ADENOSYLMETHIONINE, SMK box (SAM-III) Riboswitch, STRONTIUM ION 著者 Lu, C. 登録日 2008-08-13 公開日 2008-10-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structures of the SAM-III/S(MK) riboswitch reveal the SAM-dependent translation inhibition mechanism. Nat.Struct.Mol.Biol., 15, 2008
3E37	Protein farnesyltransferase complexed with bisubstrate ethylenediamine scaffold inhibitor 5 分子名称: Protein farnesyltransferase subunit beta, Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, ZINC ION, ... 著者 Hast, M.A, Beese, L.S. 登録日 2008-08-06 公開日 2009-03-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase. Chem.Biol., 16, 2009
3E6B	OCPA complexed CprK (C200S) 分子名称: (3-CHLORO-4-HYDROXYPHENYL)ACETIC ACID, Cyclic nucleotide-binding protein 著者 Levy, C. 登録日 2008-08-15 公開日 2008-09-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator Mol.Microbiol., 70, 2008
3N1E	Vps54 C-terminal domain 分子名称: GLYCEROL, MAGNESIUM ION, Vacuolar protein sorting-associated protein 54 著者 Perez-Victoria, F.J, Abascal-Palacios, G, Tascon, I, Kajava, A, Pioro, E.P, Bonifacino, J.S, Hierro, A. 登録日 2010-05-15 公開日 2010-07-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.702 Å) 主引用文献 Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex. Proc.Natl.Acad.Sci.USA, 107, 2010
3EAQ	Novel dimerization motif in the DEAD box RNA helicase Hera form 2, complete dimer, symmetric 分子名称: CHLORIDE ION, Heat resistant RNA dependent ATPase 著者 Klostermeier, D, Rudolph, M.G. 登録日 2008-08-26 公開日 2008-12-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A novel dimerization motif in the C-terminal domain of the Thermus thermophilus DEAD box helicase Hera confers substantial flexibility. Nucleic Acids Res., 37, 2009
8AVB	Cryo-EM structure for mouse leptin in complex with the mouse LEP-R ectodomain (1:2 mLEP:mLEPR model). 分子名称: Leptin, Leptin receptor 著者 Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. 登録日 2022-08-26 公開日 2023-04-05 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (4.43 Å) 主引用文献 Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
3EFL	Crystal structure of the VEGFR2 kinase domain in complex with motesanib 分子名称: N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide, Vascular endothelial growth factor receptor 2 著者 Kim, J.L, Whittington, D.A, Long, A.M, Rose, P, Gu, Y, Zhao, H. 登録日 2008-09-09 公開日 2009-09-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of Motesanib To be Published
3CCC	Crystal Structure of Human DPP4 in complex with a benzimidazole derivative 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile, ... 著者 Wallace, M.B, Skene, R.J. 登録日 2008-02-25 公開日 2008-10-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Structure-based design and synthesis of benzimidazole derivatives as dipeptidyl peptidase IV inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
3N5U	Crystal structure of an Rb C-terminal peptide bound to the catalytic subunit of PP1 分子名称: CHLORIDE ION, MANGANESE (II) ION, Retinoblastoma-associated protein, ... 著者 Hirschi, A.M, Cecchini, M, Steinhardt, R.C, Dick, F.A, Rubin, S.M. 登録日 2010-05-25 公開日 2010-08-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein. Nat.Struct.Mol.Biol., 17, 2010
3BT1	Structure of urokinase receptor, urokinase and vitronectin complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator, ... 著者 Huang, M. 登録日 2007-12-27 公開日 2008-03-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes Nat.Struct.Mol.Biol., 15, 2008

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