3MPH

The structure of human diamine oxidase complexed with an inhibitor aminoguanidine

Summary for 3MPH

• Entry DOI: 10.2210/pdb3mph/pdb
• Related: 3HI7 3HIG 3HII 3K5T
• Descriptor: Amiloride-sensitive amine oxidase, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: oxidoreductase, copper amine oxidase, cao, topaquinone, tpq, diamine oxidase, dao, human, aminoguanidine
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 170035.68

Authors

McGrath, A.P.,Guss, J.M. (deposition date: 2010-04-27, release date: 2010-09-08, Last modification date: 2023-11-01)

• Primary citation: McGrath, A.P.,Caradoc-Davies, T.,Collyer, C.A.,Guss, J.M.; Correlation of active site metal content in human diamine oxidase with trihydroxyphenylalanine quinone cofactor biogenesis; Biochemistry, 49:8316-8324, 2010; PubMed: 20722416; DOI: 10.1021/bi1010915

Experimental method

X-RAY DIFFRACTION (2.05 Å)