3N5U

Crystal structure of an Rb C-terminal peptide bound to the catalytic subunit of PP1

Summary for 3N5U

Entry DOI	10.2210/pdb3n5u/pdb
Descriptor	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, Retinoblastoma-associated protein, MANGANESE (II) ION, ... (4 entities in total)
Functional Keywords	retinoblastoma, prb, rb, protein phosphatase-1, pp1, phosphatase, hydrolase, transcription regulation
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: P62136 Nucleus: P06400
Total number of polymer chains	3
Total formula weight	70566.22
Authors	Hirschi, A.M.,Cecchini, M.,Steinhardt, R.C.,Dick, F.A.,Rubin, S.M. (deposition date: 2010-05-25, release date: 2010-08-11, Last modification date: 2024-02-21)
Primary citation	Hirschi, A.,Cecchini, M.,Steinhardt, R.C.,Schamber, M.R.,Dick, F.A.,Rubin, S.M. An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein. Nat.Struct.Mol.Biol., 17:1051-1057, 2010 Cited by PubMed: 20694007 DOI: 10.1038/nsmb.1868 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation