PDB: 56562 件ウェブページステータス検索Chemie searchBIRD

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5L45	polyketide ketoreductase SimC7 - apo crystal form 2 分子名称: GLYCEROL, SimC7, TETRAETHYLENE GLYCOL 著者 Schafer, M, Stevenson, C.E.M, Wilkinson, B, Lawson, D.M, Buttner, M.J. 登録日 2016-05-25 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Substrate-Assisted Catalysis in Polyketide Reduction Proceeds via a Phenolate Intermediate. Cell Chem Biol, 23, 2016
8A4W	Crystal structure of human cathepsin L with covalently bound Cathepsin L inhibitor IV 分子名称: 1,2-ETHANEDIOL, Cathepsin L, DI(HYDROXYETHYL)ETHER, ... 著者 Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. 登録日 2022-06-13 公開日 2023-07-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
8A4X	Crystal structure of human Cathepsin L with covalently bound Calpain inhibitor III 分子名称: (phenylmethyl) N-[(2S)-3-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanyl-3-phenyl-propan-2-yl]amino]butan-2-yl]carbamate, Cathepsin L, DI(HYDROXYETHYL)ETHER, ... 著者 Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. 登録日 2022-06-13 公開日 2023-07-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
6YK0	Crystal structure of mouse pyridoxal kinase in complex with ATP-gamma-S 分子名称: 1,2-ETHANEDIOL, GLYCEROL, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Kasaragod, V.B, Schindelin, H. 登録日 2020-04-05 公開日 2021-04-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Pyridoxal kinase inhibition by artemisinins down-regulates inhibitory neurotransmission. Proc.Natl.Acad.Sci.USA, 117, 2020
6YRV	Crystal structure of FAP after illumination at 100K 分子名称: CARBON DIOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, Fatty acid Photodecarboxylase, ... 著者 Sorigue, D, Gotthard, G, Blangy, S, Nurizzo, D, Royant, A, Beisson, F, Arnoux, P. 登録日 2020-04-20 公開日 2021-04-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Mechanism and dynamics of fatty acid photodecarboxylase. Science, 372, 2021
4GZ7	The crystal structure of Apo-dihydropyrimidinase from Tetraodon nigroviridis 分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, dihydropyrimidinase 著者 Hsien, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. 登録日 2012-09-06 公開日 2013-09-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Lysine Carboxylation: Metal and Structure Requirements for Post-translational Modification To be Published
6YJZ	Crystal structure of mouse pyridoxal kinase in apo form 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Pyridoxal Kinase, ... 著者 Kasaragod, V.B, Schindelin, H. 登録日 2020-04-05 公開日 2021-04-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Pyridoxal kinase inhibition by artemisinins down-regulates inhibitory neurotransmission. Proc.Natl.Acad.Sci.USA, 117, 2020
8IEO	Cryo-EM structure of ATP13A2 in the nominal E1P state 分子名称: MAGNESIUM ION, Polyamine-transporting ATPase 13A2, SPERMINE, ... 著者 Liu, Z.M, Mu, J.Q, Xue, C.Y. 登録日 2023-02-15 公開日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 Conformational cycle of human polyamine transporter ATP13A2. Nat Commun, 14, 2023
8A4U	Crystal structure of human cathepsin L with CAA0225 分子名称: (2S,3S)-N3-[2-(4-hydroxyphenyl)ethyl]-N2-[(2S)-1-oxidanylidene-3-phenyl-1-[(phenylmethyl)amino]propan-2-yl]oxirane-2,3-dicarboxamide, 1,2-ETHANEDIOL, Cathepsin L, ... 著者 Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. 登録日 2022-06-13 公開日 2023-07-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
6YK1	Crystal structure of mouse pyridoxal kinase in complex with ATP-gamma-S and artesunate 分子名称: 1,2-ETHANEDIOL, Artesunate, GLYCEROL, ... 著者 Kasaragod, V.B, Schindelin, H. 登録日 2020-04-05 公開日 2021-04-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Pyridoxal kinase inhibition by artemisinins down-regulates inhibitory neurotransmission. Proc.Natl.Acad.Sci.USA, 117, 2020
6YRU	Crystal structure of FAP in the dark at 100K 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Fatty acid Photodecarboxylase, STEARIC ACID 著者 Sorigue, D, Gotthard, G, Blangy, S, Nurizzo, D, Royant, A, Beisson, F, Arnoux, P. 登録日 2020-04-20 公開日 2021-04-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Mechanism and dynamics of fatty acid photodecarboxylase. Science, 372, 2021
6YS2	Crystal structure of FAP R451A in the dark at 100K 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Fatty acid Photodecarboxylase, STEARIC ACID 著者 Sorigue, D, Gotthard, G, Blangy, S, Nurizzo, D, Royant, A, Beisson, F, Arnoux, P. 登録日 2020-04-20 公開日 2021-04-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Mechanism and dynamics of fatty acid photodecarboxylase. Science, 372, 2021
8HYN	Bacterial STING from Riemerella anatipestifer 分子名称: CD-NTase-associated protein 12, TETRAETHYLENE GLYCOL 著者 Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. 登録日 2023-01-07 公開日 2024-01-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.089 Å) 主引用文献 Structural insights into the regulation, ligand recognition, and oligomerization of bacterial STING. Nat Commun, 14, 2023
6YRX	Low-dose crystal structure of FAP at room temperature 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Fatty acid Photodecarboxylase, STEARIC ACID 著者 Sorigue, D, Gotthard, G, Blangy, S, Nurizzo, D, Royant, A, Beisson, F, Arnoux, P. 登録日 2020-04-20 公開日 2021-04-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Mechanism and dynamics of fatty acid photodecarboxylase. Science, 372, 2021
6R7R	Crystal structure of the glutamate transporter homologue GltTk in complex with D-aspartate 分子名称: D-ASPARTIC ACID, DECYL-BETA-D-MALTOPYRANOSIDE, DI(HYDROXYETHYL)ETHER, ... 著者 Arkhipova, V, Guskov, A, Slotboom, D.J. 登録日 2019-03-29 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Binding and transport of D-aspartate by the glutamate transporter homolog Glt Tk . Elife, 8, 2019
6YRZ	Crystal structure of FAP et pH 8.5 after illumination at 150K 分子名称: CARBON DIOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, Fatty acid photodecarboxylase, ... 著者 Sorigue, D, Legrand, P, Blangy, S, Beisson, F, Arnoux, P. 登録日 2020-04-20 公開日 2021-04-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.824 Å) 主引用文献 Mechanism and dynamics of fatty acid photodecarboxylase. Science, 372, 2021
8IDR	Crystal structure of apo-form of dehydroquinate dehydratase from Corynebacterium glutamicum 分子名称: 3-dehydroquinate dehydratase, CITRATE ANION, TETRAETHYLENE GLYCOL 著者 Lee, C.H, Kim, S, Kim, K.-J. 登録日 2023-02-14 公開日 2023-12-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and Biochemical Analysis of 3-Dehydroquinate Dehydratase from Corynebacterium glutamicum . J Microbiol Biotechnol., 33, 2023
6R9S	Human Cyclophilin D in complex with bicyclic fragment 分子名称: (1~{R},9~{R},10~{S})-4-fluoranyl-12-oxa-8-azatricyclo[7.3.1.0^{2,7}]trideca-2(7),3,5-trien-10-ol, PENTAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, ... 著者 Graedler, U. 登録日 2019-04-04 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of novel Cyclophilin D inhibitors starting from three dimensional fragments with millimolar potencies. Bioorg.Med.Chem.Lett., 29, 2019
6R9U	Human Cyclophilin D in complex with fragment 分子名称: 14-ethyl-4,6-dioxa-10,14-diazatricyclo[7.6.0.0^{3,7}]pentadeca-1(9),2,7-trien-13-one, Peptidyl-prolyl cis-trans isomerase F, mitochondrial, ... 著者 Graedler, U. 登録日 2019-04-04 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Discovery of novel Cyclophilin D inhibitors starting from three dimensional fragments with millimolar potencies. Bioorg.Med.Chem.Lett., 29, 2019
5LK1	Structure of hantavirus envelope glycoprotein Gc in postfusion conformation in presence of 200 mM KCL 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelopment polyprotein, POTASSIUM ION, ... 著者 Guardado-Calvo, P, Rey, F.A. 登録日 2016-07-20 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc. Plos Pathog., 12, 2016
5LJX	Structure of hantavirus envelope glycoprotein Gc in postfusion conformation in presence of 600 mM KCL 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelopment polyprotein, POTASSIUM ION, ... 著者 Guardado-Calvo, P, Rey, F.A. 登録日 2016-07-20 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc. Plos Pathog., 12, 2016
5ISJ	Endothiapepsin in complex with chiral chlorinated primary amine fragment 分子名称: (1S)-2-amino-1-(4-chlorophenyl)ethan-1-ol, ACETATE ION, DIMETHYL SULFOXIDE, ... 著者 Radeva, N, Heine, A, Klebe, G. 登録日 2016-03-15 公開日 2017-03-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.651 Å) 主引用文献 Crystallographic Fragment Screening of an Entire Library to be published
6YS4	Structure of the Homo sapiens SAS-6 coiled-coil domain 分子名称: GLYCINE, Spindle assembly abnormal protein 6 homolog, TETRAETHYLENE GLYCOL 著者 Kantsadi, A.L, Vakonakis, I. 登録日 2020-04-21 公開日 2021-05-12 最終更新日 2022-03-16 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel. Structure, 2022
6R5H	Major aspartyl peptidase 1 from C. neoformans 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ... 著者 Krystufek, R, Sacha, P, Brynda, J, Konvalinka, J. 登録日 2019-03-25 公開日 2021-04-07 最終更新日 2021-06-09 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery. J.Med.Chem., 64, 2021
5LGJ	THE CRYSTAL STRUCTURE OF IGE FC MUTANT - P333C 分子名称: GLYCEROL, Ig epsilon chain C region, SULFATE ION, ... 著者 Dhaliwal, B, Pang, M.O.Y, Sutton, B.J. 登録日 2016-07-07 公開日 2017-03-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 THE CRYSTAL STRUCTURE OF IGE FC MUTANT - P333C To Be Published

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