6YK0

Crystal structure of mouse pyridoxal kinase in complex with ATP-gamma-S

Summary for 6YK0

Entry DOI	10.2210/pdb6yk0/pdb
Descriptor	Pyridoxal kinase, TETRAETHYLENE GLYCOL, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... (6 entities in total)
Functional Keywords	pdxk, plp, pyridoxal, atp gamma s, transferase
Biological source	Mus musculus (Mouse)
Total number of polymer chains	4
Total formula weight	144662.30
Authors	Kasaragod, V.B.,Schindelin, H. (deposition date: 2020-04-05, release date: 2021-04-14, Last modification date: 2024-01-24)
Primary citation	Kasaragod, V.B.,Pacios-Michelena, A.,Schaefer, N.,Zheng, F.,Bader, N.,Alzheimer, C.,Villmann, C.,Schindelin, H. Pyridoxal kinase inhibition by artemisinins down-regulates inhibitory neurotransmission. Proc.Natl.Acad.Sci.USA, 117:33235-33245, 2020 Cited by PubMed: 33318193 DOI: 10.1073/pnas.2008695117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation