4GZ7
 
 | | The crystal structure of Apo-dihydropyrimidinase from Tetraodon nigroviridis | | Descriptor: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, dihydropyrimidinase | | Authors: | Hsien, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. | | Deposit date: | 2012-09-06 | | Release date: | 2013-09-11 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Lysine Carboxylation: Metal and Structure Requirements for Post-translational Modification
To be Published
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4H00
 | | The crystal structure of mon-Zn dihydropyrimidinase from Tetraodon nigroviridis | | Descriptor: | ZINC ION, dihydropyrimidinase | | Authors: | Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. | | Deposit date: | 2012-09-06 | | Release date: | 2013-09-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Lysine Carboxylation: Metal and Structural Requirements for Post-translational Modification
To be Published
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4H01
 | | The crystal structure of di-Zn dihydropyrimidinase from Tetraodon nigroviridis | | Descriptor: | ZINC ION, dihydropyrimidinase | | Authors: | Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. | | Deposit date: | 2012-09-06 | | Release date: | 2013-09-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Lysine Carboxylation: Metal and Structural Requirements for Post-translational Modification
To be Published
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2M9G
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4LCR
 | | The crystal structure of di-Zn dihydropyrimidinase in complex with NCBA | | Descriptor: | Chromosome 8 SCAF14545, whole genome shotgun sequence, N-(AMINOCARBONYL)-BETA-ALANINE, ... | | Authors: | Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. | | Deposit date: | 2013-06-22 | | Release date: | 2013-09-18 | | Last modified: | 2014-02-12 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function.
J.Biol.Chem., 288, 2013
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4LCQ
 | | The crystal structure of di-Zn dihydropyrimidinase in complex with NCBI | | Descriptor: | (2S)-3-(carbamoylamino)-2-methylpropanoic acid, ZINC ION, dihydropyrimidinase | | Authors: | Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. | | Deposit date: | 2013-06-22 | | Release date: | 2013-09-18 | | Last modified: | 2014-02-12 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function.
J.Biol.Chem., 288, 2013
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4LCS
 | | The crystal structure of di-Zn dihydropyrimidinase in complex with hydantoin | | Descriptor: | Chromosome 8 SCAF14545, whole genome shotgun sequence, ZINC ION, ... | | Authors: | Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S. | | Deposit date: | 2013-06-23 | | Release date: | 2013-09-18 | | Last modified: | 2014-02-12 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function.
J.Biol.Chem., 288, 2013
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4JBP
 | | Novel Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules | | Descriptor: | 1-(4-{2-[(6-{4-[2-(4-hydroxypiperidin-1-yl)ethoxy]phenyl}furo[2,3-d]pyrimidin-4-yl)amino]ethyl}phenyl)-3-phenylurea, Aurora Kinase A | | Authors: | Wu, J.S, Leou, J.S, Peng, Y.H, Hsueh, C.C, Hsieh, H.P, Wu, S.Y. | | Deposit date: | 2013-02-20 | | Release date: | 2013-06-05 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4JBQ
 | | Novel Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules | | Descriptor: | Aurora Kinase A, CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE | | Authors: | Wu, J.S, Leou, J.S, Peng, Y.H, Hsueh, C.C, Hsieh, H.P, Wu, S.Y. | | Deposit date: | 2013-02-20 | | Release date: | 2013-06-05 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4JBO
 | | Novel Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules | | Descriptor: | 1-(4-{2-[(6-{4-[2-(dimethylamino)ethoxy]phenyl}furo[2,3-d]pyrimidin-4-yl)amino]ethyl}phenyl)-3-phenylurea, Aurora kinase A | | Authors: | Wu, J.S, Leou, J.S, Peng, Y.H, Hsueh, C.C, Hsieh, H.P, Wu, S.Y. | | Deposit date: | 2013-02-20 | | Release date: | 2013-06-05 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.493 Å) | | Cite: | Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules.
Proc.Natl.Acad.Sci.USA, 110, 2013
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6KLA
 | | Crystal structure of human c-KIT kinase domain in complex with compound 15a | | Descriptor: | Mast/stem cell growth factor receptor Kit, N-[6-(4-ethylpiperazin-1-yl)-2-methyl-pyrimidin-4-yl]-5-pyridin-4-yl-1,3-thiazol-2-amine | | Authors: | Wu, T.S, Peng, Y.H, Hsueh, C.C, Wu, S.Y. | | Deposit date: | 2019-07-30 | | Release date: | 2019-11-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.109 Å) | | Cite: | Identification of a Multitargeted Tyrosine Kinase Inhibitor for the Treatment of Gastrointestinal Stromal Tumors and Acute Myeloid Leukemia.
J.Med.Chem., 62, 2019
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