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6PO4
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2.1 Angstrom Resolution Crystal Structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN) from Haemophilus influenzae PittII.
分子名称: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE, ...
著者Minasov, G, Shuvalova, L, Cardona-Correa, A, Dubrovska, I, Grimshaw, S, Kwon, K, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-07-03
公開日2019-07-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献2.1 Angstrom Resolution Crystal Structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN) from Haemophilus influenzae PittII.
To Be Published
6PWW
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BU of 6pww by Molmil
Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome
分子名称: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U.
登録日2019-07-23
公開日2019-12-18
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Nat Commun, 10, 2019
3K8Q
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BU of 3k8q by Molmil
Crystal structure of human purine nucleoside phosphorylase in complex with SerMe-Immucillin H
分子名称: 7-({[2-hydroxy-1-(hydroxymethyl)ethyl]amino}methyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ho, M, Almo, S.C, Scharmm, V.L.
登録日2009-10-14
公開日2010-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of human nucleoside phosphorylase in complex with SerMe-ImmH
Proc.Natl.Acad.Sci.USA, 2010
5ZWM
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BU of 5zwm by Molmil
Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom (tri-snRNP and U2 snRNP Part)
分子名称: 13 kDa ribonucleoprotein-associated protein, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, ...
著者Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y.
登録日2018-05-16
公開日2018-08-29
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018
6AH0
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BU of 6ah0 by Molmil
The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者Zhan, X, Yan, C, Zhang, X, Shi, Y.
登録日2018-08-15
公開日2018-11-14
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
6AHD
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BU of 6ahd by Molmil
The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Brr2, U5 small nuclear ribonucleoprotein 200 kDa helicase, ...
著者Zhan, X, Yan, C, Zhang, X, Shi, Y.
登録日2018-08-17
公開日2018-11-14
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
6PWX
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BU of 6pwx by Molmil
Cryo-EM structure of RbBP5 bound to the nucleosome
分子名称: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U.
登録日2019-07-23
公開日2019-12-18
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Nat Commun, 10, 2019
5GT0
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BU of 5gt0 by Molmil
Crystal structure of nucleosome complex with human testis-specific histone variants, Th2a
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-A, ...
著者Kumarevel, T, Sivaraman, P.
登録日2016-08-18
公開日2017-02-15
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b
Biophys. Chem., 221, 2017
3MGR
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BU of 3mgr by Molmil
Binding of Rubidium ions to the Nucleosome Core Particle
分子名称: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
著者Mohideen, K, Muhammad, R, Davey, C.A.
登録日2010-04-07
公開日2010-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Perturbations in nucleosome structure from heavy metal association.
Nucleic Acids Res., 38, 2010
3MGS
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BU of 3mgs by Molmil
Binding of Cesium ions to the Nucleosome Core particle
分子名称: CESIUM ION, CHLORIDE ION, DNA (147-MER), ...
著者Mohideen, K, Muhammad, R, Davey, C.A.
登録日2010-04-07
公開日2010-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Perturbations in nucleosome structure from heavy metal association.
Nucleic Acids Res., 2010
3MGQ
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BU of 3mgq by Molmil
Binding of Nickel ions to the Nucleosome Core Particle
分子名称: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
著者Mohideen, K, Muhammad, R, Davey, C.A.
登録日2010-04-07
公開日2010-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Perturbations in nucleosome structure from heavy metal association.
Nucleic Acids Res., 38, 2010
3MJR
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BU of 3mjr by Molmil
Human dCK complex with Acyclic Nucleoside
分子名称: 9-HYROXYETHOXYMETHYLGUANINE, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE
著者Hazra, S, Lavie, A.
登録日2010-04-13
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Sugar Ring of the Nucleoside Is Required for Productive Substrate Positioning in the Active Site of Human Deoxycytidine Kinase (dCK): Implications for the Development of dCK-Activated Acyclic Guanine Analogues.
J.Med.Chem., 53, 2010
3MGP
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BU of 3mgp by Molmil
Binding of Cobalt ions to the Nucleosome Core Particle
分子名称: CHLORIDE ION, COBALT (II) ION, DNA (147-MER), ...
著者Mohideen, K, Muhammad, R, Davey, C.A.
登録日2010-04-07
公開日2010-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Perturbations in nucleosome structure from heavy metal association.
Nucleic Acids Res., 38, 2010
1P34
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BU of 1p34 by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
登録日2003-04-17
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
1P3L
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BU of 1p3l by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
登録日2003-04-17
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
1P3I
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BU of 1p3i by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
登録日2003-04-17
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
1P3M
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BU of 1p3m by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
登録日2003-04-17
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
1P3P
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BU of 1p3p by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
登録日2003-04-17
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
6OM3
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BU of 6om3 by Molmil
Crystal structure of the Orc1 BAH domain in complex with a nucleosome core particle
分子名称: DNA (146-MER), DNA (147-MER), Histone H2A, ...
著者De Ioannes, P.E, Wang, M, Armache, K.-J.
登録日2019-04-18
公開日2019-07-10
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure and function of the Orc1 BAH-nucleosome complex.
Nat Commun, 10, 2019
5UE1
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BU of 5ue1 by Molmil
Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase in complex with adenine from Vibrio fischeri ES114
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ...
著者Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-12-29
公開日2017-01-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Vibrio fischeri ES114
To Be Published
1KX5
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BU of 1kx5 by Molmil
X-Ray Structure of the Nucleosome Core Particle, NCP147, at 1.9 A Resolution
分子名称: CHLORIDE ION, DNA (5'(ATCAATATCCACCTGCAGATACTACCAAAAGTGTATTTGGAAACTGCTCCATCAAAAGGCATGTTCAGCTGGAATCCAGCTGAACATGCCTTTTGATGGAGCAGTTTCCAAATACACTTTTGGTAGTATCTGCAGGTGGATATTGAT)3'), DNA (5'(ATCAATATCCACCTGCAGATACTACCAAAAGTGTATTTGGAAACTGCTCCATCAAAAGGCATGTTCAGCTGGATTCCAGCTGAACATGCCTTTTGATGGAGCAGTTTCCAAATACACTTTTGGTAGTATCTGCAGGTGGATATTGAT)3'), ...
著者Davey, C.A, Sargent, D.F, Luger, K, Maeder, A.W, Richmond, T.J.
登録日2002-01-31
公開日2002-12-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Solvent Mediated Interactions in the Structure of the Nucleosome Core Particle at 1.9 A Resolution
J.Mol.Biol., 319, 2002
5ZWO
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BU of 5zwo by Molmil
Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom
分子名称: 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ...
著者Bai, R, Wan, R, Yan, C, Shi, Y.
登録日2018-05-16
公開日2018-08-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Science, 360, 2018
6OE3
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BU of 6oe3 by Molmil
Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-7-fluoro-2-naphthonitrile (JLJ635), a Non-nucleoside Inhibitor
分子名称: 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}-7-fluoronaphthalene-2-carbonitrile, HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT, ...
著者Bertoletti, N, Kudalkar, S.N, Anderson, K.S, Cisneros Trigo, J.A, Jorgensen, W.L.
登録日2019-03-27
公開日2019-05-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV.
Antiviral Res., 167, 2019
5TW3
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BU of 5tw3 by Molmil
Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)-4-fluorophenoxy)-7-fluoro-2-naphthonitrile (JLJ636), a Non-nucleoside Inhibitor
分子名称: 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]-4-fluorophenoxy}-7-fluoronaphthalene-2-carbonitrile, HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT, ...
著者Chan, A.H, Anderson, K.S.
登録日2016-11-11
公開日2017-03-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.853 Å)
主引用文献Structural and Preclinical Studies of Computationally Designed Non-Nucleoside Reverse Transcriptase Inhibitors for Treating HIV infection.
Mol. Pharmacol., 91, 2017
5FYD
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Structural and biochemical insights into 7beta-hydroxysteroid dehydrogenase stereoselectivity
分子名称: GLYCEROL, OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY PROTEIN
著者Savino, S, Ferrandi, E, Forneris, F, Rovida, S, Riva, S, Monti, D, Mattevi, A.
登録日2016-03-07
公開日2016-04-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and Biochemical Insights Into 7Beta-Hydroxysteroid Dehydrogenase Stereoselectivity.
Proteins, 84, 2016

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件を2024-11-06に公開中

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