Human dCK complex with Acyclic Nucleoside

Summary for 3MJR
DescriptorDeoxycytidine kinase, 9-HYROXYETHOXYMETHYLGUANINE, URIDINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywordsacv, gcv, dck, kinase, udp, p-loop, kinase activity, nucleoside kinase, transferase
Biological sourceHomo sapiens (human)
Cellular locationNucleus : P27707
Total number of polymer chains4
Total formula weight132582.30
Hazra, S.,Lavie, A. (deposition date: 2010-04-13, release date: 2010-07-28, Last modification date: 2017-11-08)
Primary citationHazra, S.,Konrad, M.,Lavie, A.
The Sugar Ring of the Nucleoside Is Required for Productive Substrate Positioning in the Active Site of Human Deoxycytidine Kinase (dCK): Implications for the Development of dCK-Activated Acyclic Guanine Analogues.
J.Med.Chem., 53:5792-5800, 2010
PubMed: 20684612
DOI: 110.1021/jm1005379
PDB entries with the same primary citation
Experimental method
Structure validation
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB Foundation
wwPDBRCSB PDBPDBeBMRBAdv. SearchSearch help


PDB entries from 2021-06-16