3MJR

Human dCK complex with Acyclic Nucleoside

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Deoxycytidine kinase	polymer	279	32572.5	4	UniProt (P27707) Pfam (PF01712)	Homo sapiens (human)	dCK
2	E, G, J (A, B, D)	9-HYROXYETHOXYMETHYLGUANINE	non-polymer		225.2	3	Chemie (AC2) PubChem (135398513)
3	F, H, I, K (A, B, C, D)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	4	Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (60098857) PubChem (57448939) PubChem (3084486) PubChem (91746160) PubChem (6101632) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (6604175) PubChem (11811538) PubChem (12049241)
4	L, M, N, O (A, B, C, D)	water	water		18.0	65	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 260 (UniProt: P27707)

PDB	External Database	Details
Met -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Ser 9	Cys 9	conflict
Ser 45	Cys 45	conflict
Ser 59	Cys 59	conflict
Ser 146	Cys 146	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	130290.0
Non-Polymers*	Number of molecules	7
	Total formula weight	2292.3
All*	Total formula weight	132582.3

*Water molecules are not included.