3MJR

Human dCK complex with Acyclic Nucleoside

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Deoxycytidine kinase	polymer	279	32572.5	4	UniProt (P27707) Pfam (PF01712)	Homo sapiens (human)	dCK
2	E, G, J (A, B, D)	9-HYROXYETHOXYMETHYLGUANINE	non-polymer		225.2	3	Chemie (AC2)
3	F, H, I, K (A, B, C, D)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	4	Chemie (UDP)
4	L, M, N, O (A, B, C, D)	water	water		18.0	65	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 260 (UniProt: P27707)

PDB	External Database	Details
Met -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Ser 9	Cys 9	conflict
Ser 45	Cys 45	conflict
Ser 59	Cys 59	conflict
Ser 146	Cys 146	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	130290.0
Non-Polymers*	Number of molecules	7
	Total formula weight	2292.3
All*	Total formula weight	132582.3

*Water molecules are not included.