3K8Q

Crystal structure of human purine nucleoside phosphorylase in complex with SerMe-Immucillin H

Summary for 3K8Q

• Entry DOI: 10.2210/pdb3k8q/pdb
• Related: 1RR6 1RSZ 3K8O
• Descriptor: Purine nucleoside phosphorylase, 7-({[2-hydroxy-1-(hydroxymethyl)ethyl]amino}methyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: transition state analog inhibitor, hpnp, pnp, immucillin h, serme-immh, cytoskeleton, disease mutation, glycosyltransferase, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytoskeleton : P00491
• Total number of polymer chains: 1
• Total formula weight: 32613.06

Authors

Ho, M.,Almo, S.C.,Scharmm, V.L. (deposition date: 2009-10-14, release date: 2010-03-02, Last modification date: 2024-02-21)

• Primary citation: Ho, M.,Almo, S.C.,Scharmm, V.L.; Crystal structure of human nucleoside phosphorylase in complex with SerMe-ImmH; Proc.Natl.Acad.Sci.USA, 2010

Experimental method

X-RAY DIFFRACTION (2.5 Å)