3K8Q
Crystal structure of human purine nucleoside phosphorylase in complex with SerMe-Immucillin H
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Purine nucleoside phosphorylase | polymer | 289 | 32184.9 | 1 | UniProt (P00491) Pfam (PF01048) | Homo sapiens (human) | PNP, Inosine phosphorylase |
| 2 | B (A) | 7-({[2-hydroxy-1-(hydroxymethyl)ethyl]amino}methyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one | non-polymer | 238.2 | 1 | Chemie (22A) | |||
| 3 | C, D (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | E (A) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A: 1 - 289 (UniProt: P00491)
| PDB | External Database | Details |
|---|---|---|
| Ser 51 | Gly 51 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32184.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 428.2 | |
| All* | Total formula weight | 32613.1 |
