Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants

Summary for 1P3L
Related1AOI 1F66 1ID3 1KX3 1KX4 1KX5 1P34 1P3A 1P3B 1P3F 1P3G 1P3I 1P3K 1P3M 1P3O 1P3P
DescriptorPalindromic 146bp Human Alpha-Satellite DNA fragment, Histone H3, Histone H4, ... (6 entities in total)
Functional Keywordssin mutants, nucleosome core particle, chromatin, protein/dna interaction, structural protein-dna complex, structural protein/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus: P62799 P02281
Total number of polymer chains10
Total formula weight199030.74
Muthurajan, U.M.,Bao, Y.,Forsberg, L.J.,Edayathumangalam, R.S.,Dyer, P.N.,White, C.L.,Luger, K. (deposition date: 2003-04-17, release date: 2004-02-24, Last modification date: 2011-07-13)
Primary citationBao, Y.,Dyer, P.N.,Edayathumangalam, R.S.,Forsberg, L.J.,Luger, K.,Muthurajan, U.M.,White, C.L.
Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23:260-271, 2004
PubMed: 14739929
DOI: 110.1038/sj.emboj.7600046
PDB entries with the same primary citation
Experimental method
Structure validation
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PDB entries from 2021-06-23