1P3A

Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants

Summary for 1P3A

Related1AOI 1F66 1ID3 1KX3 1KX4 1KX5 1P34 1P3B 1P3F 1P3G 1P3I 1P3K 1P3L 1P3M 1P3O 1P3P
DescriptorPalindromic 146bp Human Alpha-Satellite DNA fragment, Histone H3, Histone H4, ... (6 entities in total)
Functional Keywordssin mutants, nucleosome core particle, chromatin, protein/dna interaction, structural protein-dna complex, structural protein/dna
Biological sourceHomo sapiens (human)
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Cellular locationNucleus P62799 P02281
Total number of polymer chains10
Total molecular weight198918.56
Authors
Muthurajan, U.M.,Bao, Y.,Forsberg, L.J.,Edayathumangalam, R.S.,Dyer, P.N.,White, C.L.,Luger, K. (deposition date: 2003-04-17, release date: 2004-02-24, Last modification date: 2011-07-13)
Primary citation
Muthurajan, U.M.,Bao, Y.,Forsberg, L.J.,Edayathumangalam, R.S.,Dyer, P.N.,White, C.L.,Luger, K.
Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23:260-271, 2004
PubMed: 14739929 (PDB entries with the same primary citation)
DOI: 10.1038/sj.emboj.7600046
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers200.5%5.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution