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1EGJ
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BU of 1egj by Molmil
DOMAIN 4 OF THE BETA COMMON CHAIN IN COMPLEX WITH AN ANTIBODY
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (HEAVY CHAIN), ANTIBODY (LIGHT CHAIN), ...
著者Rossjohn, J, McKinstry, W.J, Woodcock, J.M, McClure, B.J, Hercus, T.R, Parker, M.W, Lopez, A.F, Bagley, C.J.
登録日2000-02-15
公開日2001-02-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common beta-chain bound to an antagonist.
Blood, 95, 2000
4A7S
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BU of 4a7s by Molmil
Structure of human I113T SOD1 mutant complexed with 5-Fluorouridine in the p21 space group
分子名称: 5-FLUOROURIDINE, ACETATE ION, COPPER (II) ION, ...
著者Wright, G.S.A, Kershaw, N.M, Antonyuk, S.V, Strange, R.W, ONeil, P.M, Hasnain, S.S.
登録日2011-11-14
公開日2012-12-05
最終更新日2013-05-08
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Ligand Binding and Aggregation of Pathogenic Sod1.
Nat.Commun., 4, 2013
6EI2
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BU of 6ei2 by Molmil
Crystal Structure of HLA-A68 presenting a C-terminally extended peptide
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, CADMIUM ION, ...
著者Picaud, S, Guillaume, P, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gfeller, D, Filippakopoulos, P.
登録日2017-09-16
公開日2017-10-11
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Crystal Structure of HLA-A68 presenting a C-terminally extended peptide
To Be Published
4A7V
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Structure of human I113T SOD1 mutant complexed with dopamine in the p21 space group
分子名称: COPPER (II) ION, L-DOPAMINE, SULFATE ION, ...
著者Wright, G.S.A, Antonyuk, S.V, Kershaw, N.M, Strange, R.W, Hasnain, S.S.
登録日2011-11-14
公開日2012-11-28
最終更新日2013-05-08
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Ligand Binding and Aggregation of Pathogenic Sod1.
Nat.Commun., 4, 2013
6G3J
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BU of 6g3j by Molmil
MHC A02 Allele presenting MTSAIGILVP
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Rizkallah, P.J, Sewell, A.K.
登録日2018-03-26
公開日2019-02-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Peptide Super-Agonist Enhances T-Cell Responses to Melanoma.
Front Immunol, 10, 2019
7N73
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BU of 7n73 by Molmil
Cryo-EM structure of ATP13A2 in the ADP-AlF-bound E1P-ADP-like state
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHOLESTEROL HEMISUCCINATE, Isoform 3 of Polyamine-transporting ATPase 13A2, ...
著者Sim, S.I, Park, E.
登録日2021-06-09
公開日2021-11-10
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7N72
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Cryo-EM structure of ATP13A2 in the AlF-bound E2-Pi-like state
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, ...
著者Sim, S.I, Park, E.
登録日2021-06-09
公開日2021-11-10
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7N75
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Cryo-EM structure of ATP13A2 D458N/D962N mutant in the E1-apo state, Conformation 1
分子名称: Isoform 3 of Polyamine-transporting ATPase 13A2
著者Sim, S.I, Park, E.
登録日2021-06-09
公開日2021-11-10
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7N76
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BU of 7n76 by Molmil
Cryo-EM structure of ATP13A2 D458N/D962N mutant in the E1-apo state, Conformation 2
分子名称: Isoform 3 of Polyamine-transporting ATPase 13A2
著者Sim, S.I, Park, E.
登録日2021-06-09
公開日2021-11-10
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7N77
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BU of 7n77 by Molmil
Cryo-EM structure of ATP13A2 D458N/D962N mutant in the AlF-bound E1P-like state
分子名称: CHOLESTEROL HEMISUCCINATE, Isoform 3 of Polyamine-transporting ATPase 13A2, MAGNESIUM ION, ...
著者Sim, S.I, Park, E.
登録日2021-06-09
公開日2021-11-10
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7N74
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BU of 7n74 by Molmil
Cryo-EM structure of ATP13A2 D508N mutant in the E1-ATP-like state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL HEMISUCCINATE, Isoform 3 of Polyamine-transporting ATPase 13A2, ...
著者Sim, S.I, Park, E.
登録日2021-06-09
公開日2021-11-10
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7N70
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BU of 7n70 by Molmil
Cryo-EM structure of ATP13A2 in the BeF-bound E2P-like state
分子名称: BERYLLIUM TRIFLUORIDE ION, CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, ...
著者Sim, S.I, Park, E.
登録日2021-06-09
公開日2021-11-10
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7N78
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BU of 7n78 by Molmil
Cryo-EM structure of ATP13A2 in the E2-Pi state
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, ...
著者Sim, S.I, Park, E.
登録日2021-06-09
公開日2021-11-10
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
3EUF
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BU of 3euf by Molmil
Crystal structure of BAU-bound human uridine phosphorylase 1
分子名称: 1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE, PHOSPHATE ION, Uridine phosphorylase 1
著者Roosild, T.P.
登録日2008-10-10
公開日2009-03-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapy.
Bmc Struct.Biol., 9, 2009
6G4W
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BU of 6g4w by Molmil
Cryo-EM structure of a late human pre-40S ribosomal subunit - State A
分子名称: 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ...
著者Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R.
登録日2018-03-28
公開日2018-06-06
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
6E1I
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BU of 6e1i by Molmil
HLA-A*0201 single chain trimer with murine H2K alpha 3 domain and HPV.16 E7 peptide YMLDLQPET
分子名称: HLA-A*0201 single chain trimer with murine H2K alpha 3 domain and HPV.16 E7 peptide YMLDLQPET
著者Finton, K.A.K, Rusnac, D.V.
登録日2018-07-09
公開日2019-07-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Effects of HLA single chain trimer design on peptide presentation and stability
To Be Published
6E0E
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BU of 6e0e by Molmil
Crystal structure of Glucokinase in complex with compound 6
分子名称: 2-({2-[(4-methyl-1,3-thiazol-2-yl)amino]pyridin-3-yl}oxy)benzonitrile, Glucokinase, alpha-D-glucopyranose
著者Hinklin, R.J, Baer, B.R, Boyd, S.A, Chicarelli, M.D, Condroski, K.R, DeWolf, W.E, Fischer, J, Frank, M, Hingorani, G.P, Lee, P.A, Neitzel, N.A, Pratt, S.A, Singh, A, Sullivan, F.X, Turner, T, Voegtli, W.C, Wallace, E.M, Williams, L, Aicher, T.D.
登録日2018-07-06
公開日2019-07-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery and preclinical development of AR453588 as an anti-diabetic glucokinase activator.
Bioorg.Med.Chem., 28, 2020
6G9L
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BU of 6g9l by Molmil
Structure of homomeric mLRRC8A volume-regulated anion channel at 5.01 A resolution
分子名称: Volume-regulated anion channel subunit LRRC8A
著者Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R.
登録日2018-04-11
公開日2018-05-16
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (5.01 Å)
主引用文献Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018
6G51
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BU of 6g51 by Molmil
Cryo-EM structure of a late human pre-40S ribosomal subunit - State D
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R.
登録日2018-03-28
公開日2018-06-06
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Visualizing late states of human 40S ribosomal subunit maturation.
Nature, 558, 2018
3GQF
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BU of 3gqf by Molmil
Structural and Biophysical Properties of the Pathogenic SOD1 Variant H46R/H48Q
分子名称: CALCIUM ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Winkler, D.D, Schuermann, J.P, Hart, P.J.
登録日2009-03-24
公開日2009-04-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and biophysical properties of the pathogenic SOD1 variant H46R/H48Q.
Biochemistry, 48, 2009
6G9R
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BU of 6g9r by Molmil
Murine class I major histocompatibility complex H-2 Db in complex with self-antigen derived from dopamine monooxygenase.
分子名称: Beta-2-microglobulin, Dopamine beta-hydroxylase, H-2 class I histocompatibility antigen, ...
著者Achour, A, Sandalova, T, Allerbring, E.
登録日2018-04-11
公開日2019-04-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for CD8+ T cells auto-reactivity in LCMV infection
to be published
6GY0
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BU of 6gy0 by Molmil
mPI3Kd IN COMPLEX WITH AZ3
分子名称: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, ~{N}-[4-methyl-5-(1-oxidanylidene-7-sulfamoyl-isoindol-5-yl)-1,3-thiazol-2-yl]ethanamide
著者Petersen, J.
登録日2018-06-27
公開日2019-02-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献A class of highly selective inhibitors bind to an active state of PI3K gamma.
Nat.Chem.Biol., 15, 2019
3SJU
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BU of 3sju by Molmil
Hedamycin Polyketide Ketoreductase bound to NADPH
分子名称: Keto reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Javidpour, P, Tsai, S.-C.
登録日2011-06-21
公開日2011-09-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Biochemical Studies of the Hedamycin Type II Polyketide Ketoreductase (HedKR): Molecular Basis of Stereo- and Regiospecificities.
Biochemistry, 50, 2011
4R1R
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BU of 4r1r by Molmil
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH SUBSTRATE, GDP AND EFFECTOR DTTP FROM ESCHERICHIA COLI
分子名称: GUANOSINE-5'-DIPHOSPHATE, RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN, ...
著者Eriksson, M, Eklund, H.
登録日1997-07-22
公開日1998-01-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding.
Structure, 5, 1997
3HFF
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BU of 3hff by Molmil
Monomeric human Cu,Zn Superoxide dismutase without Zn ligands
分子名称: Superoxide dismutase [Cu-Zn], ZINC ION
著者Saraboji, K, Nordlund, A, Leinartait, L, Oliveberg, M, Logan, D.T.
登録日2009-05-11
公開日2009-06-16
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Functional features cause misfolding of the ALS-provoking enzyme SOD1.
Proc.Natl.Acad.Sci.USA, 106, 2009

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