4A7V

Structure of human I113T SOD1 mutant complexed with dopamine in the p21 space group

Summary for 4A7V

Entry DOI	10.2210/pdb4a7v/pdb
Related	1AZV 1BA9 1DSW 1FUN 1HL4 1HL5 1KMG 1L3N 1MFM 1N18 1N19 1OEZ 1OZT 1OZU 1P1V 1PTZ 1PU0 1RK7 1SOS 1SPD 1UXL 1UXM 2AF2 2C9S 2C9U 2C9V 2V0A 2VR6 2VR7 2VR8 2WKO 2WYT 2WYZ 2WZ0 2WZ5 2WZ6 2XJK 2XJL 4A7G 4A7Q 4A7R 4A7S 4A7T 4A7U 4SOD
Descriptor	SUPEROXIDE DISMUTASE [CU-ZN], L-DOPAMINE, SULFATE ION, ... (6 entities in total)
Functional Keywords	oxidoreductase, amyotrophic lateral sclerosis, antioxidant, disease mutation, metal-binding, oxioreductase, zn superoxide dismutase
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: P00441
Total number of polymer chains	2
Total formula weight	32426.36
Authors	Wright, G.S.A.,Antonyuk, S.V.,Kershaw, N.M.,Strange, R.W.,Hasnain, S.S. (deposition date: 2011-11-14, release date: 2012-11-28, Last modification date: 2013-05-08)
Primary citation	Wright, G.S.A.,Antonyuk, S.V.,Kershaw, N.M.,Strange, R.W.,Hasnain, S.S. Ligand Binding and Aggregation of Pathogenic Sod1. Nat.Commun., 4:1758-, 2013 Cited by PubMed: 23612299 DOI: 10.1038/NCOMMS2750 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1 Å)

Structure validation