2VR6
Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.3 A resolution
Summary for 2VR6
Entry DOI | 10.2210/pdb2vr6/pdb |
Related | 1AZV 1BA9 1DSW 1FUN 1HL4 1HL5 1KMG 1L3N 1MFM 1N18 1N19 1OEZ 1OZT 1OZU 1P1V 1PTZ 1PU0 1RK7 1SOS 1SPD 1UXL 1UXM 2AF2 2C9S 2C9U 2C9V 2V0A 4SOD |
Descriptor | SUPEROXIDE DISMUTASE [CU-ZN], COPPER (II) ION, ZINC ION, ... (6 entities in total) |
Functional Keywords | oxidoreductase, zinc, copper, human cu, cytoplasm, acetylation, ubl conjugation, disease mutation, zn superoxide dismutase, amyotrophic lateral sclerosis, antioxidant, metal-binding |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: P00441 |
Total number of polymer chains | 2 |
Total formula weight | 32494.34 |
Authors | Antonyuk, S.,Cao, X.,Seetharaman, S.V.,Whitson, L.J.,Taylor, A.B.,Holloway, S.P.,Strange, R.W.,Doucette, P.A.,Tiwari, A.,Hayward, L.J.,Padua, S.,Cohlberg, J.A.,Selverstone Valentine, J.,Hasnain, S.S.,Hart, P.J. (deposition date: 2008-03-28, release date: 2008-04-15, Last modification date: 2023-12-13) |
Primary citation | Cao, X.,Antonyuk, S.,Seetharaman, S.V.,Whitson, L.J.,Taylor, A.B.,Holloway, S.P.,Strange, R.W.,Doucette, P.A.,Valentine, J.S.,Tiwari, A.,Hayward, L.J.,Padua, S.,Cohlberg, J.A.,Hasnain, S.S.,Hart, P.J. Structures of the G85R Variant of Sod1 in Familial Amyotrophic Lateral Sclerosis. J.Biol.Chem., 283:16169-, 2008 Cited by PubMed: 18378676DOI: 10.1074/JBC.M801522200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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