2WZ0
L38V SOD1 mutant complexed with aniline.
Summary for 2WZ0
Entry DOI | 10.2210/pdb2wz0/pdb |
Related | 1AZV 1BA9 1DSW 1FUN 1HL4 1HL5 1KMG 1L3N 1MFM 1N18 1N19 1OEZ 1OZT 1OZU 1P1V 1PTZ 1PU0 1RK7 1SOS 1SPD 1UXL 1UXM 2AF2 2C9S 2C9U 2C9V 2V0A 2VR6 2VR7 2VR8 2WKO 2WYT 2WYZ 4SOD |
Descriptor | SUPEROXIDE DISMUTASE [CU-ZN], COPPER (II) ION, ZINC ION, ... (8 entities in total) |
Functional Keywords | oxidoreductase, disease mutation, amyotrophic lateral sclerosis, antioxidant |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm : P00441 |
Total number of polymer chains | 2 |
Total formula weight | 32600.10 |
Authors | Antonyuk, S.,Strange, R.W.,Hasnain, S.S. (deposition date: 2009-11-20, release date: 2010-12-08, Last modification date: 2024-10-09) |
Primary citation | Antonyuk, S.,Strange, R.W.,Hasnain, S.S. Structural Discovery of Small Molecule Binding Sites in Cu-Zn Human Superoxide Dismutase Familial Amyotrophic Lateral Sclerosis Mutants Provides Insights for Lead Optimization. J.Med.Chem., 53:1402-, 2010 Cited by PubMed: 20067275DOI: 10.1021/JM9017948 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.72 Å) |
Structure validation
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