3EUF
Crystal structure of BAU-bound human uridine phosphorylase 1
Summary for 3EUF
Entry DOI | 10.2210/pdb3euf/pdb |
Related | 3EUE |
Descriptor | Uridine phosphorylase 1, 1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | nucleoside phosphorylase, uridine rescue, 5-benzylacyclouridine, alternative splicing, glycosyltransferase, transferase |
Biological source | Homo sapiens |
Total number of polymer chains | 4 |
Total formula weight | 145687.50 |
Authors | Roosild, T.P. (deposition date: 2008-10-10, release date: 2009-03-31, Last modification date: 2023-09-06) |
Primary citation | Roosild, T.P.,Castronovo, S.,Fabbiani, M.,Pizzorno, G. Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapy. Bmc Struct.Biol., 9:14-14, 2009 Cited by PubMed: 19291308DOI: 10.1186/1472-6807-9-14 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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