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5C2F
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BU of 5c2f by Molmil
K428A mutant nuclease domain of the large terminase subunit gp2 of bacterial virus Sf6 with Manganese and beta-thujaplicinol
分子名称: 2,7-dihydroxy-4-(propan-2-yl)cyclohepta-2,4,6-trien-1-one, Gene 2 protein, MANGANESE (II) ION
著者Zhao, H, Tang, L.
登録日2015-06-15
公開日2015-10-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism.
Nucleic Acids Res., 43, 2015
2J85
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BU of 2j85 by Molmil
B116 of Sulfolobus turreted icosahedral virus (STIV)
分子名称: STIV B116
著者Larson, E.T, Reiter, D, Young, M.J, Lawrence, C.M.
登録日2006-10-19
公開日2006-11-02
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献A New DNA Binding Protein Highly Conserved in Diverse Crenarchaeal Viruses
Virology, 363, 2007
2IG0
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BU of 2ig0 by Molmil
Structure of 53BP1/methylated histone peptide complex
分子名称: Dimethylated Histone H4-K20 peptide, SULFATE ION, Tumor suppressor p53-binding protein 1
著者Mer, G.
登録日2006-09-22
公開日2007-01-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair.
Cell(Cambridge,Mass.), 127, 2006
7NYY
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BU of 7nyy by Molmil
Cryo-EM structure of the MukBEF monomer
分子名称: 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, Chromosome partition protein MukB, ...
著者Buermann, F, Lowe, J.
登録日2021-03-23
公開日2021-07-07
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites.
Mol.Cell, 81, 2021
7NZ4
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BU of 7nz4 by Molmil
Cryo-EM structure of the MukBEF dimer
分子名称: 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, Chromosome partition protein MukB, ...
著者Buermann, F, Lowe, J.
登録日2021-03-23
公開日2021-07-07
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (13 Å)
主引用文献Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites.
Mol.Cell, 81, 2021
2JPB
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BU of 2jpb by Molmil
Solution Structure of OMPR-C DNA Binding Protein
分子名称: Transcriptional regulatory protein ompR
著者Liao, X, Kenney, L, Liao, W, Integrated Center for Structure and Function Innovation (ISFI)
登録日2007-05-03
公開日2007-06-12
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Solution Structure of OMPR-C DNA Binding Protein
To be Published
7TUJ
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BU of 7tuj by Molmil
NMR solution structure of the phosphorylated MUS81-binding region from human SLX4
分子名称: Structure-specific endonuclease subunit SLX4
著者Payliss, B.J, Reichheld, S.E, Lemak, A, Arrowsmith, C.H, Sharpe, S, Wyatt, H.D.M.
登録日2022-02-02
公開日2022-10-19
最終更新日2022-11-09
実験手法SOLUTION NMR
主引用文献Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease.
Cell Rep, 41, 2022
5CR5
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BU of 5cr5 by Molmil
X-RAY CRYSTAL STRUCTURE AT 1.61A RESOLUTION OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH A BIPHENYL PYRROLIDINE ETHER COMPOUND AND AN INTERNAL ALDIMINE LINKED PLP COFACTOR.
分子名称: 1,2-ETHANEDIOL, 3-({(3R)-1-[(5-bromothiophen-2-yl)carbonyl]pyrrolidin-3-yl}oxy)-N-methyl-2'-[(methylsulfonyl)amino]biphenyl-4-carboxamide, Branched-chain-amino-acid aminotransferase, ...
著者Somers, D.O.
登録日2015-07-22
公開日2015-08-12
最終更新日2015-09-02
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library.
Acs Med.Chem.Lett., 6, 2015
6FXA
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BU of 6fxa by Molmil
Dimerization domain of TP901-1 CI repressor
分子名称: CI, SULFATE ION
著者Varming, A.K, Rasmussen, K.K, Lo Leggio, L.
登録日2018-03-08
公開日2018-05-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of the bacteriophage TP901-1 CI repressor dimerization and interaction with DNA.
FEBS Lett., 592, 2018
6KDN
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BU of 6kdn by Molmil
HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dGTP ternary complex
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ...
著者Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K.
登録日2019-07-02
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine.
Sci Rep, 10, 2020
5C10
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BU of 5c10 by Molmil
Nuclease domain of the large terminase subunit gp2 of bacterial virus Sf6
分子名称: Gene 2 protein
著者Zhao, H, Tang, L.
登録日2015-06-12
公開日2015-10-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism.
Nucleic Acids Res., 43, 2015
5C2D
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BU of 5c2d by Molmil
K428A mutant gp2c of large terminase subunit from bacteriophage sf6 with calcium
分子名称: CALCIUM ION, Gene 2 protein
著者Zhao, H, Tang, L.
登録日2015-06-15
公開日2015-10-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism.
Nucleic Acids Res., 43, 2015
453D
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BU of 453d by Molmil
5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'-BENZIMIDAZOLE COMPLEX
分子名称: 4-{[4-HYDROXY-PHENYL]-1H-BENZIMIDAZOLE-5-YL}-BENZIMIDAZOLE-2-YL-[4-HYDROXY-BENZENE], DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
著者Neidle, S.
登録日1999-02-18
公開日2000-05-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Symmetric bis-benzimidazoles, a new class of sequence-selective DNA-binding molecules
J.Chem.Soc.,Chem.Commun., 1999
6IFO
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BU of 6ifo by Molmil
Crystal structure of AcrIIA2-SpyCas9-sgRNA ternary complex
分子名称: AcrIIA2, CRISPR-associated endonuclease Cas9/Csn1, RNA (99-MER)
著者Liu, L, Wang, Y.
登録日2018-09-20
公開日2019-01-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.313 Å)
主引用文献Phage AcrIIA2 DNA Mimicry: Structural Basis of the CRISPR and Anti-CRISPR Arms Race.
Mol. Cell, 73, 2019
2KUO
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BU of 2kuo by Molmil
Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response
分子名称: Aprataxin and PNK-like factor, ZINC ION
著者Li, G.Y, McCulloch, R.D, Fenton, A, Cheung, M, Meng, L, Ikura, M, Koch, C.A.
登録日2010-02-23
公開日2010-05-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and identification of ADP-ribose recognition motifs of aprataxin PNK-like factor (APLF) required for the interaction with sites of DNA damage response
To be Published
5C15
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BU of 5c15 by Molmil
K428A mutant nuclease domain of the large terminase subunit gp2 of bacterial virus Sf6 with Manganese
分子名称: Gene 2 protein, MANGANESE (II) ION
著者Zhao, H, Tang, L.
登録日2015-06-12
公開日2015-10-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism.
Nucleic Acids Res., 43, 2015
6KDK
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BU of 6kdk by Molmil
HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dCTP ternary complex
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ...
著者Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K.
登録日2019-07-02
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine.
Sci Rep, 10, 2020
7NPD
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BU of 7npd by Molmil
Vibiro cholerae ParA2
分子名称: Walker A-type ATPase
著者Parker, A.V, Bergeron, J.R.C.
登録日2021-02-26
公開日2021-05-19
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The structure of the bacterial DNA segregation ATPase filament reveals the conformational plasticity of ParA upon DNA binding.
Nat Commun, 12, 2021
7Z4J
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BU of 7z4j by Molmil
SpCas9 bound to 18-nucleotide complementary DNA substrate in the catalytic state
分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, Non-target strand of 18-nucleotide complementary DNA substrate, ...
著者Pacesa, M, Jinek, M.
登録日2022-03-03
公開日2022-08-31
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
7YMO
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BU of 7ymo by Molmil
Crystal structure of the recombination mediator protein RecO from Campylobacter jejuni
分子名称: Recombination protein RecO, ZINC ION
著者Lee, S, Oh, H.B, Yoon, S.I.
登録日2022-07-29
公開日2022-08-31
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Recombination Mediator Protein RecO from Campylobacter jejuni and Its Interaction with DNA and a Zinc Ion.
Int J Mol Sci, 23, 2022
3VA3
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BU of 3va3 by Molmil
Crystal structure of RNase T in complex with a duplex DNA product (stem loop DNA with 2 nucleotide 3' overhang)
分子名称: COBALT (II) ION, DNA (5'-D(*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*TP*T)-3'), Ribonuclease T
著者Hsiao, Y.-Y, Yuan, H.S.
登録日2011-12-28
公開日2012-07-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.714 Å)
主引用文献How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
6IK9
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BU of 6ik9 by Molmil
HIV-1 reverse transcriptase with Q151M/G112S/D113A/Y115F/F116Y/F160L/I159L:DNA:dGTP ternary complex
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ...
著者Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K.
登録日2018-10-15
公開日2019-01-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.435 Å)
主引用文献Active-site deformation in the structure of HIV-1 RT with HBV-associated septuple amino acid substitutions rationalizes the differential susceptibility of HIV-1 and HBV against 4'-modified nucleoside RT inhibitors.
Biochem. Biophys. Res. Commun., 509, 2019
3HG8
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BU of 3hg8 by Molmil
Crystal Structure of 5-SMe Derivatized DNA
分子名称: 5'-D(*GP*(UMS)P*GP*(US2)P*AP*CP*AP*C)-3'
著者Sheng, J, Hassan, A.E.A, Zhang, W, Huang, Z.
登録日2009-05-13
公開日2009-07-21
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate
Chemistryselect, 8, 2023
8CIL
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BU of 8cil by Molmil
Crystal structure of Coxiella burnetii Fic protein 2
分子名称: Fic family protein
著者Hoepfner, D, Itzen, A, Pogenberg, V.
登録日2023-02-10
公開日2023-11-15
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献The DNA-binding induced (de)AMPylation activity of a Coxiella burnetii Fic enzyme targets Histone H3.
Commun Biol, 6, 2023
1WTU
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BU of 1wtu by Molmil
TRANSCRIPTION FACTOR 1, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: TRANSCRIPTION FACTOR 1
著者Jia, X, Grove, A, Ivancic, M, Hsu, V.L, Geiduschek, E.P, Kearns, D.R.
登録日1996-07-29
公開日1997-02-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the Bacillus subtilis phage SPO1-encoded type II DNA-binding protein TF1 in solution.
J.Mol.Biol., 263, 1996

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