7TUJ

NMR solution structure of the phosphorylated MUS81-binding region from human SLX4

Summary for 7TUJ

• Entry DOI: 10.2210/pdb7tuj/pdb
• Related: 6VWB
• NMR Information: BMRB: 30986
• Descriptor: Structure-specific endonuclease subunit SLX4 (1 entity in total)
• Functional Keywords: sap domain, disorder-to-order transition, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 9956.20

Authors

Payliss, B.J.,Reichheld, S.E.,Lemak, A.,Arrowsmith, C.H.,Sharpe, S.,Wyatt, H.D.M. (deposition date: 2022-02-02, release date: 2022-10-19, Last modification date: 2022-11-09)

• Primary citation: Payliss, B.J.,Tse, Y.W.E.,Reichheld, S.E.,Lemak, A.,Yun, H.Y.,Houliston, S.,Patel, A.,Arrowsmith, C.H.,Sharpe, S.,Wyatt, H.D.M.; Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease.; Cell Rep, 41:111537-111537, 2022; PubMed: 36288699; DOI: 10.1016/j.celrep.2022.111537

Experimental method

SOLUTION NMR