2IG0

Structure of 53BP1/methylated histone peptide complex

Summary for 2IG0

Entry DOI	10.2210/pdb2ig0/pdb
Descriptor	Tumor suppressor p53-binding protein 1, Dimethylated Histone H4-K20 peptide, SULFATE ION, ... (4 entities in total)
Functional Keywords	tandem tudor domains, dimethylated histone h4, dna repair, cell cycle regulation, cell cycle
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q12888
Total number of polymer chains	2
Total formula weight	15395.47
Authors	Mer, G. (deposition date: 2006-09-22, release date: 2007-01-02, Last modification date: 2011-07-13)
Primary citation	Botuyan, M.V.,Lee, J.,Ward, I.M.,Kim, J.E.,Thompson, J.R.,Chen, J.,Mer, G. Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair. Cell(Cambridge,Mass.), 127:1361-1373, 2006 Cited by PubMed: 17190600 DOI: 10.1016/j.cell.2006.10.043 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation