6IFO

Crystal structure of AcrIIA2-SpyCas9-sgRNA ternary complex

Summary for 6IFO

Entry DOI	10.2210/pdb6ifo/pdb
Descriptor	CRISPR-associated endonuclease Cas9/Csn1, RNA (99-MER), AcrIIA2 (3 entities in total)
Functional Keywords	anti-crispr, spycas9, sgrna, acriia2, rna binding protein-rna complex, rna binding protein/rna
Biological source	Streptococcus pyogenes serotype M1 More
Total number of polymer chains	6
Total formula weight	409899.00
Authors	Liu, L.,Wang, Y. (deposition date: 2018-09-20, release date: 2019-01-23, Last modification date: 2023-11-22)
Primary citation	Liu, L.,Yin, M.,Wang, M.,Wang, Y. Phage AcrIIA2 DNA Mimicry: Structural Basis of the CRISPR and Anti-CRISPR Arms Race. Mol. Cell, 73:611-620.e3, 2019 Cited by PubMed: 30606466 DOI: 10.1016/j.molcel.2018.11.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.313 Å)

Structure validation