PDB: 13258 件ウェブページステータス検索Chemie searchBIRD

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6K00	Crystal structure A of ceNAP1-H2A-H2B complex 分子名称: Histone H2B 1,Histone H2A, Nucleosome Assembly Protein 著者 Liu, Y.R. 登録日 2019-05-05 公開日 2019-10-09 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.198 Å) 主引用文献 Crystal structure of xlH2A-H2B Structure, 2019
1S1C	Crystal structure of the complex between the human RhoA and Rho-binding domain of human ROCKI 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rho-associated, ... 著者 Dvorsky, R, Blumenstein, L, Vetter, I.R, Ahmadian, M.R. 登録日 2004-01-06 公開日 2004-02-10 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Insights into the Interaction of ROCKI with the Switch Regions of RhoA. J.Biol.Chem., 279, 2004
8G3D	48-nm doublet microtubule from Tetrahymena thermophila strain K40R 分子名称: B2B3_fMIP, B5B6_fMIP, CFAM166A, ... 著者 Black, C.S, Kubo, S, Yang, S.K, Bui, K.H. 登録日 2023-02-07 公開日 2023-06-14 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins. Nat Commun, 14, 2023
8G2Z	48-nm doublet microtubule from Tetrahymena thermophila strain CU428 分子名称: B2B3_fMIP, B5B6_fMIP, CFAM166A, ... 著者 Black, C.S, Kubo, S, Yang, S.K, Bui, K.H. 登録日 2023-02-06 公開日 2023-06-14 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins. Nat Commun, 14, 2023
6HQY	Crystal structure of Schistosoma mansoni HDAC8 complexed with PCI-34051 分子名称: 1-[(4-methoxyphenyl)methyl]-~{N}-oxidanyl-indole-6-carboxamide, GLYCEROL, Histone deacetylase, ... 著者 Marek, M, Shaik, T.B, Romier, C. 登録日 2018-09-25 公開日 2018-10-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
6H0U	Glycogen synthase kinase-3 beta (GSK3) complex with a covalent [1,2,4]triazolo[1,5-a][1,3,5]triazine inhibitor 分子名称: (2~{R})-3-[7-azanyl-5-(cyclohexylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-2-yl]-2-cyano-propanamide, CHLORIDE ION, GLYCEROL, ... 著者 Marcovich, I, Demitri, N, De Zorzi, R, Storici, P. 登録日 2018-07-10 公開日 2019-05-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A Triazolotriazine-Based Dual GSK-3 beta /CK-1 delta Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition. Chemmedchem, 14, 2019
6H1I	Crystal structure of human Pirin in complex with bisamide compound 2 分子名称: FE (III) ION, GLYCEROL, Pirin, ... 著者 Ali, S, Le Bihan, Y.V, van Montfort, R.L.M. 登録日 2018-07-11 公開日 2018-11-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Privileged Structures and Polypharmacology within and between Protein Families. ACS Med Chem Lett, 9, 2018
3PVB	Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase 分子名称: GLYCEROL, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Boettcher, A.J, Wu, J, Kim, C, Yang, J, Bruystens, J, Cheung, N, Pennypacker, J.K, Blumenthal, D.A, Kornev, A.P, Taylor, S.S. 登録日 2010-12-06 公開日 2011-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase Structure, 19, 2011
1NZ8	Solution Structure of the N-utilization substance G (NusG) N-terminal (NGN) domain from Thermus thermophilus 分子名称: TRANSCRIPTION ANTITERMINATION PROTEIN NUSG 著者 Reay, P, Yamasaki, K, Terada, T, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-02-17 公開日 2004-04-06 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural and sequence comparisons arising from the solution structure of the transcription elongation factor NusG from Thermus thermophilus Proteins, 56, 2004
1B00	PHOB RECEIVER DOMAIN FROM ESCHERICHIA COLI 分子名称: PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB 著者 Sola, M, Gomis-Ruth, F.X, Serrano, L, Gonzalez, A, Coll, M. 登録日 1998-11-15 公開日 1999-11-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Three-dimensional crystal structure of the transcription factor PhoB receiver domain. J.Mol.Biol., 285, 1999
6HSG	Crystal structure of Schistosoma mansoni HDAC8 H292M mutant complexed with NCC-149 分子名称: DIMETHYLFORMAMIDE, GLYCEROL, Histone deacetylase, ... 著者 Shaik, T.B, Marek, M, Romier, C. 登録日 2018-10-01 公開日 2018-10-31 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.846 Å) 主引用文献 Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
6K02	Crystal structure of ceNAP1 core 分子名称: Nucleosome Assembly Protein, ZINC ION 著者 Liu, Y.R. 登録日 2019-05-05 公開日 2019-10-09 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.162 Å) 主引用文献 Crystal structure of xlH2A-H2B Structure, 2019
6K7P	Crystal structure of human AFF4-THD domain 分子名称: AF4/FMR2 family member 4 著者 Tang, D, Xue, Y, Li, S, Cheng, W, Duan, J, Wang, J, Qi, S. 登録日 2019-06-08 公開日 2020-03-11 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and functional insight into the effect of AFF4 dimerization on activation of HIV-1 proviral transcription. Cell Discov, 6, 2020
1L0O	Crystal Structure of the Bacillus stearothermophilus Anti-Sigma Factor SpoIIAB with the Sporulation Sigma Factor SigmaF 分子名称: ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, MAGNESIUM ION, ... 著者 Campbell, E.A, Masuda, S, Sun, J.L, Muzzin, O, Olson, C.A, Wang, S, Darst, S.A. 登録日 2002-02-12 公開日 2002-04-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of the Bacillus stearothermophilus anti-sigma factor SpoIIAB with the sporulation sigma factor sigmaF. Cell(Cambridge,Mass.), 108, 2002
6K5W	Solution structure of the chromodomain of yeast Eaf3 分子名称: Chromatin modification-related protein EAF3 著者 Okuda, M, Nishimura, Y. 登録日 2019-05-31 公開日 2020-02-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The Eaf3 chromodomain acts as a pH sensor for gene expression by altering its binding affinity for histone methylated-lysine residues. Biosci.Rep., 40, 2020
1N4M	Structure of Rb tumor suppressor bound to the transactivation domain of E2F-2 分子名称: Retinoblastoma Pocket, Transcription factor E2F2 著者 Lee, C, Chang, J.H, Lee, H.S, Cho, Y. 登録日 2002-10-31 公開日 2003-01-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor GENES DEV., 16, 2002
6HRQ	Crystal structure of Schistosoma mansoni HDAC8 complexed with NCC-149 分子名称: DIMETHYLFORMAMIDE, GLYCEROL, Histone deacetylase, ... 著者 Shaik, T.B, Marek, M, Romier, C. 登録日 2018-09-28 公開日 2018-10-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.845 Å) 主引用文献 Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
6HTI	Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 6 分子名称: GLYCEROL, Histone deacetylase, POTASSIUM ION, ... 著者 Shaik, T.B, Marek, M, Romier, C. 登録日 2018-10-04 公開日 2018-10-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.693 Å) 主引用文献 Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
6HTT	Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 7 分子名称: DIMETHYLFORMAMIDE, GLYCEROL, Histone deacetylase, ... 著者 Shaik, T.B, Marek, M, Romier, C. 登録日 2018-10-04 公開日 2018-10-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.748 Å) 主引用文献 Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
7VTQ	Cryo-EM structure of mouse NLRP3 (full-length) dodecamer 分子名称: 1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea, ADENOSINE-5'-DIPHOSPHATE, NACHT, ... 著者 Ohto, U, Shimizu, T. 登録日 2021-10-30 公開日 2022-03-09 最終更新日 2022-03-23 実験手法 ELECTRON MICROSCOPY (3.55 Å) 主引用文献 Structural basis for the oligomerization-mediated regulation of NLRP3 inflammasome activation. Proc.Natl.Acad.Sci.USA, 119, 2022
7VDU	The structure of cyclin-dependent kinase 2 (CDK2) in complex with Compound 1 分子名称: Cyclin-dependent kinase 2, [1-[3-fluoranyl-4-[(2-piperidin-4-yloxy-1,6-naphthyridin-7-yl)amino]phenyl]pyrazol-3-yl]methanol 著者 Malojcic, G, Clugston, S.L, Daniels, M, Harmange, J.C, Ledeborer, M. 登録日 2021-09-07 公開日 2022-03-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Discovery and Optimization of Highly Selective Inhibitors of CDK5. J.Med.Chem., 65, 2022
6HGO	Crystal Structure of human IL-17F 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17F, ... 著者 Rondeau, J.M, Goepfert, A. 登録日 2018-08-23 公開日 2019-11-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling. Immunity, 52, 2020
1NMV	Solution structure of human Pin1 分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Bayer, E, Goettsch, S, Mueller, J.W, Griewel, B, Guiberman, E, Mayr, L, Bayer, P. 登録日 2003-01-11 公開日 2003-08-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural Analysis of the Mitotic Regulator hPin1 in Solution: INSIGHTS INTO DOMAIN ARCHITECTURE AND SUBSTRATE BINDING. J.Biol.Chem., 278, 2003
1NOW	Human lysosomal beta-hexosaminidase isoform B in complex with (2R,3R,4S,5R)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium Chloride (GalNAc-isofagomine) 分子名称: (2R,3R,4S,5R)-2-ACETAMIDO-3,4-DIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Mark, B.L, Mahuran, D.J, Cherney, M.M, Zhao, D, Knapp, S, James, M.N.G. 登録日 2003-01-16 公開日 2003-04-29 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of Human beta-hexosaminidase B: Understanding the molecular basis of Sandhoff and Tay-Sachs disease J.Mol.Biol., 327, 2003
1NZ9	Solution Structure of the N-utilization substance G (NusG) C-terminal (NGC) domain from Thermus thermophilus 分子名称: TRANSCRIPTION ANTITERMINATION PROTEIN NUSG 著者 Reay, P, Yamasaki, K, Terada, T, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-02-17 公開日 2004-04-06 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural and sequence comparisons arising from the solution structure of the transcription elongation factor NusG from Thermus thermophilus Proteins, 56, 2004

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