6K7P

Crystal structure of human AFF4-THD domain

Summary for 6K7P

• Entry DOI: 10.2210/pdb6k7p/pdb
• Descriptor: AF4/FMR2 family member 4 (2 entities in total)
• Functional Keywords: super elongation complex, aff4, hiv-1, dimerizaiton, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 30469.62

Authors

Tang, D.,Xue, Y.,Li, S.,Cheng, W.,Duan, J.,Wang, J.,Qi, S. (deposition date: 2019-06-08, release date: 2020-03-11, Last modification date: 2024-03-27)

• Primary citation: Tang, D.,Chen, C.,Liao, G.,Liu, J.,Liao, B.,Huang, Q.,Chen, Q.,Zhao, J.,Jiang, H.,Duan, J.,Huang, J.,Wang, K.,Wang, J.,Zhou, C.,Chu, W.,Li, W.,Sun, B.,Li, Z.,Dai, L.,Fu, X.,Cheng, W.,Xue, Y.,Qi, S.; Structural and functional insight into the effect of AFF4 dimerization on activation of HIV-1 proviral transcription.; Cell Discov, 6:7-7, 2020; PubMed: 32128251; DOI: 10.1038/s41421-020-0142-6

Experimental method

X-RAY DIFFRACTION (2.4 Å)