1S1C
Crystal structure of the complex between the human RhoA and Rho-binding domain of human ROCKI
Summary for 1S1C
Entry DOI | 10.2210/pdb1s1c/pdb |
Descriptor | Transforming protein RhoA, Rho-associated, coiled-coil containing protein kinase 1, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | coiled-coil, gtpase, rho kinase, rock, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side: P61586 Cytoplasm: Q13464 |
Total number of polymer chains | 4 |
Total formula weight | 59211.46 |
Authors | Dvorsky, R.,Blumenstein, L.,Vetter, I.R.,Ahmadian, M.R. (deposition date: 2004-01-06, release date: 2004-02-10, Last modification date: 2024-02-14) |
Primary citation | Dvorsky, R.,Blumenstein, L.,Vetter, I.R.,Ahmadian, M.R. Structural Insights into the Interaction of ROCKI with the Switch Regions of RhoA. J.Biol.Chem., 279:7098-7104, 2004 Cited by PubMed: 14660612DOI: 10.1074/jbc.M311911200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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