1S1C
Crystal structure of the complex between the human RhoA and Rho-binding domain of human ROCKI
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transforming protein RhoA | polymer | 183 | 20611.6 | 2 | UniProt (P61586) Pfam (PF00071) | Homo sapiens (human) | H12 |
| 2 | C, D (X, Y) | Rho-associated, coiled-coil containing protein kinase 1 | polymer | 71 | 8447.6 | 2 | UniProt (Q13464) Pfam (PF08912) | Homo sapiens (human) | p160ROCK, p160-ROCK |
| 3 | E, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | F, H (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 2 | Chemie (GNP) | |||
| 5 | I, J, K, L (A, B, X, Y) | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 181 (UniProt: P61586)
X, Y: 947 - 1015 (UniProt: Q13464)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 945 | - | cloning artifact |
| Ser 946 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 58118.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1093.0 | |
| All* | Total formula weight | 59211.5 |
