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6D78
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The complex between high-affinity TCR DMF5(alpha-D26Y,beta-L98W) and human Class I MHC HLA-A2 with the bound MART-1(27-35)peptide
分子名称: Beta-2-microglobulin, DMF5 alpha chain,DMF5 alpha chain, DMF5 beta chain,DMF5 beta chain, ...
著者Hellman, L.M, Singh, N.K.
登録日2018-04-24
公開日2019-04-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.347 Å)
主引用文献Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.
Mol. Ther., 27, 2019
6DKP
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BU of 6dkp by Molmil
The complex among DMF5(alpha-D26Y, alpha-Y50A,beta-L98W) TCR, human Class I MHC HLA-A2 and MART-1(26-35)(A27L) peptide
分子名称: Beta-2-microglobulin, DMF5 T-cell Receptor Alpha Chain fusion, DMF5 T-cell Receptor Beta Chain fusion, ...
著者Hellman, L.M, Singh, N.K.
登録日2018-05-30
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.966 Å)
主引用文献Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.
Mol. Ther., 27, 2019
6DC3
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BU of 6dc3 by Molmil
RSV prefusion F bound to RSD5 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab RSD5-Germline Heavy Chain, Fab RSD5-Germline Light Chain, ...
著者Battles, M.B, McLellan, J.S, Jones, H.J.
登録日2018-05-04
公開日2019-07-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.501 Å)
主引用文献Alternative conformations of a major antigenic site on RSV F.
Plos Pathog., 15, 2019
6DID
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BU of 6did by Molmil
HIV Env BG505 SOSIP with polyclonal Fabs from immunized rabbit #3417 post-boost#1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Turner, H.L, Cottrell, C.A, Oyen, D, Wilson, I.A, Ward, A.B.
登録日2018-05-23
公開日2018-09-05
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.71 Å)
主引用文献Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization.
Immunity, 49, 2018
8DVG
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BU of 8dvg by Molmil
Structure of KRAS WT(7-16)-HLA-A*03:01
分子名称: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, HLA class I histocompatibility antigen, ...
著者Wright, K.M, Miller, M, Gabelli, S.B.
登録日2022-07-28
公開日2023-07-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen.
Nat Commun, 14, 2023
8DNT
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BU of 8dnt by Molmil
SARS-CoV-2 specific T cell receptor
分子名称: Beta-2-microglobulin, MHC class I antigen alpha chain, Nucleoprotein, ...
著者Gallagher, D.T, Wu, D, Gowthaman, R, Pierce, B.G, Mariuzza, R.A, Weng, N.P.
登録日2022-07-11
公開日2023-07-19
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献SARS-CoV-2 infection establishes a stable and age-independent CD8 + T cell response against a dominant nucleocapsid epitope using restricted T cell receptors.
Nat Commun, 14, 2023
8EC5
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BU of 8ec5 by Molmil
Structures of HLA-B8E76C loaded with long peptides reveal novel features at the N-terminus of the groove
分子名称: Beta-2-microglobulin, MHC class I antigen, peptide RARARARARARAFVKKKYCL
著者Li, L, Bouvier, M.
登録日2022-09-01
公開日2023-07-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing.
Nat Commun, 14, 2023
8E13
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BU of 8e13 by Molmil
Structures of HLA-B8E76C loaded with long peptides reveal novel features at the N-terminus of the groove
分子名称: Beta-2-microglobulin, MHC class I antigen, PHE-ALA-LYS-LYS-LYS-TYR-CYS-LEU
著者Li, L, Bouvier, M.
登録日2022-08-09
公開日2023-07-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing.
Nat Commun, 14, 2023
8E8I
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BU of 8e8i by Molmil
Structures of HLA-B8E76C loaded with long peptides reveal novel features at the N-terminus of the groove
分子名称: Beta-2-microglobulin, MHC class I antigen, PHE-VAL-LYS-LYS-LYS-TYR-CYS-LEU
著者Li, L, Bouvier, M.
登録日2022-08-25
公開日2023-07-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing.
Nat Commun, 14, 2023
8E2Z
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BU of 8e2z by Molmil
Structures of HLA-B8E76C loaded with long peptides reveal novel features at the N-terminus of the groove
分子名称: ALA-PHE-ALA-LYS-LYS-LYS-TYR-CYS-LEU, Beta-2-microglobulin, MHC class I protein (Fragment)
著者Li, L, Bouvier, M.
登録日2022-08-16
公開日2023-08-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing.
Nat Commun, 14, 2023
6RPB
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BU of 6rpb by Molmil
Crystal structure of the T-cell receptor NYE_S1 bound to HLA A2*01-SLLMWITQV
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Coles, C.H, Mulvaney, R, Malla, S, Lloyd, A, Smith, K, Chester, F, Knox, A, Stacey, A.R, Dukes, J, Baston, E, Griffin, S, Vuidepot, A, Jakobsen, B.K, Harper, S.
登録日2019-05-14
公開日2020-01-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex.
J Immunol., 204, 2020
6RP9
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BU of 6rp9 by Molmil
Crystal structure of the T-cell receptor NYE_S3 bound to HLA A2*01-SLLMWITQV
分子名称: Beta-2-microglobulin, Cancer/testis antigen 1, HLA class I histocompatibility antigen, ...
著者Coles, C.H, Mulvaney, R, Malla, S, Lloyd, A, Smith, K, Chester, F, Knox, A, Stacey, A.R, Dukes, J, Baston, E, Griffin, S, Vuidepot, A, Jakobsen, B.K, Harper, S.
登録日2019-05-14
公開日2020-01-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex.
J Immunol., 204, 2020
8JV0
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BU of 8jv0 by Molmil
Crystal structure of the SLA-2*1001 allele and ASFV antigenic peptide at 2.2A resolution
分子名称: Beta-2-microglobulin, MHC class I antigen, TYR-MET-ASN-CYS-SER-LEU-PRO-THR-TYR
著者Wang, S.
登録日2023-06-27
公開日2024-06-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the SLA-2*1001 allele and ASFV antigenic peptide at 2.2A resolution
To Be Published
8F5A
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BU of 8f5a by Molmil
Crystal Structure of KS1 TCR in complex with HLA-B*57:01-TW10
分子名称: ACETATE ION, Beta-2-microglobulin, CHLORIDE ION, ...
著者Chatzileontiadou, D.S.M, Lobos, C.A, Gras, S.
登録日2022-11-12
公開日2024-05-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of KS1 TCR in complex with HLA-B*57:01-TW10
To Be Published
8EMA
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BU of 8ema by Molmil
mouse full length B cell receptor
分子名称: Anti-human Langerin 2G3 lambda chain, B-cell antigen receptor complex-associated protein alpha chain, B-cell antigen receptor complex-associated protein beta chain, ...
著者Ying, D, Xiong, P, Michael, R.
登録日2022-09-27
公開日2022-11-16
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (8.2 Å)
主引用文献Structural principles of B cell antigen receptor assembly.
Nature, 612, 2022
6RPA
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BU of 6rpa by Molmil
Crystal structure of the T-cell receptor NYE_S2 bound to HLA A2*01-SLLMWITQV
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Coles, C.H, Mulvaney, R, Malla, S, Lloyd, A, Smith, K, Chester, F, Knox, A, Stacey, A.R, Dukes, J, Baston, E, Griffin, S, Vuidepot, A, Jakobsen, B.K, Harper, S.
登録日2019-05-14
公開日2020-01-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex.
J Immunol., 204, 2020
8PJE
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BU of 8pje by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAT
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
著者MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Hesketh, S.J, Cole, D.K, Rizkallah, P.J, Godkin, A.J.
登録日2023-06-23
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation.
Cell Rep, 43, 2024
8PJF
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BU of 8pjf by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting P11T->R modified influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAR
分子名称: 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ...
著者MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Cole, D.K, Rizkallah, P.J, Godkin, A.J.
登録日2023-06-23
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation.
Cell Rep, 43, 2024
8PJG
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BU of 8pjg by Molmil
F11 TCR in complex with Human Leukocyte Antigen class II allotype DR1 presenting P11T->R modified influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAR
分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, HLA class II histocompatibility antigen, ...
著者MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Cole, D.K, Rizkallah, P.J, Godkin, A.J.
登録日2023-06-23
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation.
Cell Rep, 43, 2024
6SSA
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BU of 6ssa by Molmil
Human Leukocyte Antigen Class I A02 Carrying LLWNGPMQV
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, CALCIUM ION, ...
著者Rizkallah, P.J, Bovay, A.
登録日2019-09-06
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Identification of a superagonist variant of the immunodominant Yellow fever virus epitope NS4b214-222by combinatorial peptide library screening.
Mol.Immunol., 125, 2020
6SS9
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BU of 6ss9 by Molmil
Human Leukocyte Antigen Class I A02 Carrying LLWNGPMHV
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者Rizkallah, P.J, Bovay, A.
登録日2019-09-06
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Identification of a superagonist variant of the immunodominant Yellow fever virus epitope NS4b214-222by combinatorial peptide library screening.
Mol.Immunol., 125, 2020
6SS8
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BU of 6ss8 by Molmil
Human Leukocyte Antigen Class I A02 Carrying LLWNGPIAV
分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Beta-2-microglobulin, ...
著者Rizkallah, P.J, Bovay, A.
登録日2019-09-06
公開日2020-07-15
最終更新日2020-07-22
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Identification of a superagonist variant of the immunodominant Yellow fever virus epitope NS4b214-222by combinatorial peptide library screening.
Mol.Immunol., 125, 2020
6R2L
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NYBR1-A2-SLSKILDTV
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, ...
著者Rizkallah, P.J, Cole, D.K, Sami, M.
登録日2019-03-18
公開日2020-02-26
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献NYBR1-A2-SLSKILDTV
To Be Published
6R2U
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BU of 6r2u by Molmil
Zinc-alpha2-Glycoprotein with a Fluorescent Dansyl C 11 Fatty Acid
分子名称: 11-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)undecanoic acid, AZIDE ION, SULFATE ION, ...
著者Lau, A.M, Gor, J, Perkins, S.J, Coker, A.R, McDermott, L.C.
登録日2019-03-18
公開日2019-09-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Crystal structure of zinc-alpha 2-glycoprotein in complex with a fatty acid reveals multiple different modes of protein-lipid binding.
Biochem.J., 476, 2019
8QFY
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BU of 8qfy by Molmil
Crystal structure of high affinity TCR in complex with pHLA harbouring bacterial peptide
分子名称: ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Pengelly, R.J, Robinson, R.A.
登録日2023-09-05
公開日2024-05-15
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis.
Proc.Natl.Acad.Sci.USA, 121, 2024

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件を2024-07-10に公開中

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