8QFY

Crystal structure of high affinity TCR in complex with pHLA harbouring bacterial peptide

This is a non-PDB format compatible entry.

Summary for 8QFY

• Entry DOI: 10.2210/pdb8qfy/pdb
• Descriptor: HLA class I histocompatibility antigen, alpha chain E, Beta-2-microglobulin, Peptide from inhA, ... (7 entities in total)
• Functional Keywords: t-cell receptor, hla-e, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 189031.57

Authors

Pengelly, R.J.,Robinson, R.A. (deposition date: 2023-09-05, release date: 2024-05-15)

• Primary citation: Paterson, R.L.,La Manna, M.P.,Arena De Souza, V.,Walker, A.,Gibbs-Howe, D.,Kulkarni, R.,Fergusson, J.R.,Mulakkal, N.C.,Monteiro, M.,Bunjobpol, W.,Dembek, M.,Martin-Urdiroz, M.,Grant, T.,Barber, C.,Garay-Baquero, D.J.,Tezera, L.B.,Lowne, D.,Britton-Rivet, C.,Pengelly, R.,Chepisiuk, N.,Singh, P.K.,Woon, A.P.,Powlesland, A.S.,McCully, M.L.,Caccamo, N.,Salio, M.,Badami, G.D.,Dorrell, L.,Knox, A.,Robinson, R.,Elkington, P.,Dieli, F.,Lepore, M.,Leonard, S.,Godinho, L.F.; An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis.; Proc.Natl.Acad.Sci.USA, 121:e2318003121-e2318003121, 2024; PubMed: 38691588; DOI: 10.1073/pnas.2318003121

Experimental method

X-RAY DIFFRACTION (2.33 Å)