8PJE
Human Leukocyte Antigen class II allotype DR1 presenting influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAT
Summary for 8PJE
Entry DOI | 10.2210/pdb8pje/pdb |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1 beta chain, Hemagglutinin, ... (7 entities in total) |
Functional Keywords | hla-ii, hla-dr, hla-dr1, human leukocyte antigen, major histocompatibility complex, major histocompatibility complex class 2, influenza a virus, flu, haemagglutinin, ha, infection, vaccine, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 94278.32 |
Authors | MacLachlan, B.J.,Wall, A.,Greenshields-Watson, A.L.,Hesketh, S.J.,Cole, D.K.,Rizkallah, P.J.,Godkin, A.J. (deposition date: 2023-06-23, release date: 2024-06-19) |
Primary citation | Hulin-Curtis, S.,Geary, J.K.,MacLachlan, B.J.,Altmann, D.M.,Baillon, L.,Cole, D.K.,Greenshields-Watson, A.,Hesketh, S.J.,Humphreys, I.R.,Jones, I.M.,Lauder, S.N.,Mason, G.H.,Smart, K.,Scourfield, D.O.,Scott, J.,Sukhova, K.,Stanton, R.J.,Wall, A.,Rizkallah, P.J.,Barclay, W.S.,Gallimore, A.,Godkin, A. A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation. Cell Rep, 43:114259-114259, 2024 Cited by PubMed: 38819988DOI: 10.1016/j.celrep.2024.114259 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report