8PJE
Human Leukocyte Antigen class II allotype DR1 presenting influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAT
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | HLA class II histocompatibility antigen, DR alpha chain | polymer | 186 | 21562.4 | 2 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) In PDB | Homo sapiens (human) | MHC class II antigen DRA |
2 | B, E | HLA class II histocompatibility antigen, DRB1 beta chain | polymer | 194 | 22487.2 | 2 | UniProt (P01911) Pfam (PF00969) Pfam (PF07654) In PDB | Homo sapiens (human) | Human leukocyte antigen DRB1,HLA-DRB1 |
3 | C, F | Hemagglutinin | polymer | 13 | 1506.8 | 2 | UniProt (P03435) In PDB | Influenza A virus | |
4 | D, A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
5 | C, D, A, E, B... | 1,2-ETHANEDIOL | non-polymer | 62.1 | 27 | Chemie (EDO) | |||
6 | C, A, E, B | GLYCEROL | non-polymer | 92.1 | 11 | Chemie (GOL) | |||
7 | water | water | 18.0 | 571 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 182 (UniProt: P01903)
B, E: 1 - 190 (UniProt: P01911)
PDB | External Database | Details |
---|---|---|
Met -3 | - | initiating methionine |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
Met 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met -3 | - | initiating methionine |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
Met 0 | - | expression tag |
Leu 11 | Pro 40 | variant |
Phe 13 | Arg 42 | variant |
Leu 26 | Phe 55 | variant |
Glu 28 | Asp 57 | variant |
Cys 30 | Tyr 59 | variant |
Ile 31 | Phe 60 | variant |
Tyr 47 | Phe 76 | variant |
Leu 67 | Ile 96 | variant |
Arg 71 | Ala 100 | variant |
Gly 86 | Val 115 | variant |
Glu 96 | Gln 125 | variant |
Arg 133 | Leu 162 | variant |
Val 142 | Met 171 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 91112.8 | |
Non-Polymers* | Number of molecules | 40 |
Total formula weight | 3165.5 | |
All* | Total formula weight | 94278.3 |