8DNT

SARS-CoV-2 specific T cell receptor

This is a non-PDB format compatible entry.

Summary for 8DNT

• Entry DOI: 10.2210/pdb8dnt/pdb
• Descriptor: T-cell receptor alpha chain, T-cell receptor beta chain, Nucleoprotein, ... (5 entities in total)
• Functional Keywords: tcr complex, mhc, hla, sars-cov-2, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 20
• Total formula weight: 379023.57

Authors

Gallagher, D.T.,Wu, D.,Gowthaman, R.,Pierce, B.G.,Mariuzza, R.A.,Weng, N.P. (deposition date: 2022-07-11, release date: 2023-07-19, Last modification date: 2024-01-31)

• Primary citation: Choy, C.,Chen, J.,Li, J.,Gallagher, D.T.,Lu, J.,Wu, D.,Zou, A.,Hemani, H.,Baptiste, B.A.,Wichmann, E.,Yang, Q.,Ciffelo, J.,Yin, R.,McKelvy, J.,Melvin, D.,Wallace, T.,Dunn, C.,Nguyen, C.,Chia, C.W.,Fan, J.,Ruffolo, J.,Zukley, L.,Shi, G.,Amano, T.,An, Y.,Meirelles, O.,Wu, W.W.,Chou, C.K.,Shen, R.F.,Willis, R.A.,Ko, M.S.H.,Liu, Y.T.,De, S.,Pierce, B.G.,Ferrucci, L.,Egan, J.,Mariuzza, R.,Weng, N.P.; SARS-CoV-2 infection establishes a stable and age-independent CD8 + T cell response against a dominant nucleocapsid epitope using restricted T cell receptors.; Nat Commun, 14:6725-6725, 2023; PubMed: 37872153; DOI: 10.1038/s41467-023-42430-z

Experimental method

X-RAY DIFFRACTION (3.18 Å)