6NY6
 
 | | Structure of dimeric Escherichia coli toxin YoeB bound to the Thermus thermophilus 30S ribosome | | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M. | | 登録日 | 2019-02-11 | | 公開日 | 2019-08-21 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.74 Å) | | 主引用文献 | Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
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6NSH
 | | Modified ASL proline bound to Thermus thermophilus 70S (near-cognate) | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M. | | 登録日 | 2019-01-24 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.397 Å) | | 主引用文献 | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
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6O3M
 | | Unmodified tRNA(Pro) bound to Thermus thermophilus 70S (cognate) | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M. | | 登録日 | 2019-02-26 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.97 Å) | | 主引用文献 | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
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6O97
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with propylamycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.75A resolution | | 分子名称: | (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxyc yclohexyl 2-amino-2,4-dideoxy-4-propyl-alpha-D-glucopyranoside, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | | 著者 | Matsushita, T, Sati, G.C, Kondasinghe, N, Pirrone, M.G, Kato, T, Waduge, P, Kumar, H.S, Sanchon, A.C, Dobosz-Bartoszek, M, Shcherbakov, D, Juhas, M, Hobbie, S.N, Schrepfer, T, Chow, C.S, Polikanov, Y.S, Schacht, J, Vasella, A, Bottger, E.C, Crich, D. | | 登録日 | 2019-03-13 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Enterobacteriaceae and Other Gram-Negative Pathogens.
J. Am. Chem. Soc., 141, 2019
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6O9K
 | | 70S initiation complex | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Frank, J, Gonzalez Jr, R.L, kaledhonkar, S, Fu, Z, Caban, K, Li, W, Chen, B, Sun, M. | | 登録日 | 2019-03-14 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Late steps in bacterial translation initiation visualized using time-resolved cryo-EM.
Nature, 570, 2019
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6OKK
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6OT3
 | | RF2 accommodated state bound Release complex 70S at 24 ms | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | | 登録日 | 2019-05-02 | | 公開日 | 2019-06-19 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
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6OLI
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6O90
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6ORL
 | | RF1 pre-accommodated 70S complex at 24 ms | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | | 登録日 | 2019-04-30 | | 公開日 | 2019-06-19 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
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6OST
 | | RF2 pre-accommodated state bound Release complex 70S at 24ms | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | | 登録日 | 2019-05-02 | | 公開日 | 2019-06-19 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
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6OG7
 | | 70S termination complex with RF2 bound to the UGA codon. Non-rotated ribosome with RF2 bound (Structure II) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. | | 登録日 | 2019-04-01 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Extensive ribosome and RF2 rearrangements during translation termination.
Elife, 8, 2019
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6OSI
 | | Unmodified tRNA(Pro) bound to Thermus thermophilus 70S (near cognate) | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M. | | 登録日 | 2019-05-01 | | 公開日 | 2020-10-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (4.14 Å) | | 主引用文献 | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
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6OLZ
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6OM7
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6ORE
 | | Release complex 70S | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Fu, Z. | | 登録日 | 2019-04-30 | | 公開日 | 2019-06-19 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
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6O8Y
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6OLG
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6OUO
 | | RF2 accommodated state bound 70S complex at long incubation time | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | | 登録日 | 2019-05-05 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
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6OM6
 | | Structure of trans-translation inhibitor bound to E. coli 70S ribosome with P site tRNA | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Hoffer, E.D, Mehrani, A, Keiler, K.C, Stagg, S.M, Dunham, C.M. | | 登録日 | 2019-04-18 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-09-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo.
Nat Commun, 12, 2021
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6OXA
 | | Dimeric E.coli YoeB bound to Thermus thermophilus 70S pre-cleavage (AAU) | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M. | | 登録日 | 2019-05-13 | | 公開日 | 2019-08-21 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
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6P5J
 | | Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 2) | | 分子名称: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | | 著者 | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | | 登録日 | 2019-05-30 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
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6P4H
 | | Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus IRES (Class 2) | | 分子名称: | 18S rRNA, IAPV-IRES, RACK1, ... | | 著者 | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | | 登録日 | 2019-05-27 | | 公開日 | 2019-09-18 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
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6P5I
 | | Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 1) | | 分子名称: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | | 著者 | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | | 登録日 | 2019-05-30 | | 公開日 | 2019-09-18 | | 最終更新日 | 2020-02-26 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
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6P4G
 | | Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus IRES (Class 1) | | 分子名称: | 18S rRNA, IAPV-IRES, RACK1, ... | | 著者 | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | | 登録日 | 2019-05-27 | | 公開日 | 2019-09-18 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
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