6OM6

Structure of trans-translation inhibitor bound to E. coli 70S ribosome with P site tRNA

This is a non-PDB format compatible entry.

Summary for 6OM6

• Entry DOI: 10.2210/pdb6om6/pdb
• EMDB information: 20121
• Descriptor: 23S ribosomal RNA, 50S ribosomal protein L6, 50S ribosomal protein L9, ... (55 entities in total)
• Functional Keywords: trans-translation, translation, antibiotic, ribosome
• Biological source: Escherichia coli; More
• Total number of polymer chains: 54
• Total formula weight: 2164378.90

Authors

Hoffer, E.D.,Mehrani, A.,Keiler, K.C.,Stagg, S.M.,Dunham, C.M. (deposition date: 2019-04-18, release date: 2021-02-10, Last modification date: 2021-09-22)

• Primary citation: Aron, Z.D.,Mehrani, A.,Hoffer, E.D.,Connolly, K.L.,Srinivas, P.,Torhan, M.C.,Alumasa, J.N.,Cabrera, M.,Hosangadi, D.,Barbor, J.S.,Cardinale, S.C.,Kwasny, S.M.,Morin, L.R.,Butler, M.M.,Opperman, T.J.,Bowlin, T.L.,Jerse, A.,Stagg, S.M.,Dunham, C.M.,Keiler, K.C.; trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo.; Nat Commun, 12:1799-1799, 2021; PubMed: 33741965; DOI: 10.1038/s41467-021-22012-7

Experimental method

ELECTRON MICROSCOPY (3.1 Å)