6X71
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7MHD
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![BU of 7mhd by Molmil](/molmil-images/mine/7mhd) | Thioesterase Domain of Human Fatty Acid Synthase (FASN-TE) binding a competitive inhibitor SBP-7635 | 分子名称: | Fatty acid synthase, N,N-diethyl-4-{2-[(2-fluorophenyl)methyl]-1,3-thiazol-4-yl}benzene-1-sulfonamide | 著者 | Aleshin, A.E, Lambert, L, Liddington, R.C, Cosford, N. | 登録日 | 2021-04-15 | 公開日 | 2022-04-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Thioesterase Domain of Human Fatty Acid Synthase (FASN-TE) binding a competitive inhibitor SBP-7635 To Be Published
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3VGX
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![BU of 3vgx by Molmil](/molmil-images/mine/3vgx) | Structure of gp41 T21/Cp621-652 | 分子名称: | ACETIC ACID, Envelope glycoprotein gp160, GLYCEROL | 著者 | Yao, X, Waltersperger, S, Wang, M, Cui, S. | 登録日 | 2011-08-22 | 公開日 | 2012-04-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Discovery of critical residues for viral entry and inhibition through structural Insight of HIV-1 fusion inhibitor CP621-652. J.Biol.Chem., 287, 2012
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4GID
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![BU of 4gid by Molmil](/molmil-images/mine/4gid) | Structure of beta-secretase complexed with inhibitor | 分子名称: | Beta-secretase 1, L-PROLINAMIDE, N-[(2S)-1-({(2S,3R)-3-hydroxy-1-[(2-methylpropyl)amino]-1-oxobutan-2-yl}amino)-3-phenylpropan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide | 著者 | Ghosh, A, Tang, J, Venkateswara, R.K, Yadav, N, Anderson, D, Gavande, N, Huang, X, Terzyan, S. | 登録日 | 2012-08-08 | 公開日 | 2012-10-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-based design of highly selective beta-secretase inhibitors: synthesis, biological evaluation, and protein-ligand X-ray crystal structure. J.Med.Chem., 55, 2012
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7MHA
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7MN0
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7MKV
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7MKC
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7MMQ
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5KHZ
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![BU of 5khz by Molmil](/molmil-images/mine/5khz) | PSEUDO T4 LYSOZYME | 分子名称: | 2-HYDROXYETHYL DISULFIDE, Endolysin | 著者 | Scholfield, M.R. | 登録日 | 2016-06-16 | 公開日 | 2017-04-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Structure-Energy Relationships of Halogen Bonds in Proteins. Biochemistry, 56, 2017
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7MP4
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![BU of 7mp4 by Molmil](/molmil-images/mine/7mp4) | Crystal structure of Epiphyas postvittana antennal carboxylesterase 24 | 分子名称: | Carboxylesterase-24, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Hamiaux, C, Carraher, C. | 登録日 | 2021-05-04 | 公開日 | 2022-05-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Structure of an antennally-expressed carboxylesterase suggests lepidopteran odorant degrading enzymes are broadly tuned Curr Res Insect Sci, 3, 2023
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7MQP
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![BU of 7mqp by Molmil](/molmil-images/mine/7mqp) | E. coli dihydrofolate reductase complexed with 4'-chloro-3'-(4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl)-[1,1'-biphenyl]-4-carboxamide (UCP1228) | 分子名称: | 3'-[(2S)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-4'-methyl[1,1'-biphenyl]-4-carboxamide, Dihydrofolate reductase, SULFATE ION | 著者 | Lombardo, M.N, Wright, D.L. | 登録日 | 2021-05-06 | 公開日 | 2022-05-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens. Commun Biol, 5, 2022
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7MRI
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5K0W
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![BU of 5k0w by Molmil](/molmil-images/mine/5k0w) | Crystal structure of the metallo-beta-lactamase GOB-18 from Elizabethkingia meningoseptica | 分子名称: | CHLORIDE ION, Class B carbapenemase GOB-18, GLYCEROL, ... | 著者 | Buschiazzo, A, Larrieux, N, Vila, A.J, Lisa, M.N, Moran-Barrio, J. | 登録日 | 2016-05-17 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Crystal Structure of the Metallo-beta-Lactamase GOB in the Periplasmic Dizinc Form Reveals an Unusual Metal Site. Antimicrob.Agents Chemother., 60, 2016
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7MW8
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4G0M
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![BU of 4g0m by Molmil](/molmil-images/mine/4g0m) | Crystal structure of Arabidopsis thaliana AGO2 MID domain | 分子名称: | Protein argonaute 2, SULFATE ION | 著者 | Frank, F, Hauver, J, Sonenberg, N, Nagar, B. | 登録日 | 2012-07-09 | 公開日 | 2012-07-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.306 Å) | 主引用文献 | Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs. Embo J., 31, 2012
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4G0Q
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![BU of 4g0q by Molmil](/molmil-images/mine/4g0q) | Crystal structure of Arabidopsis thaliana AGO1 MID domain in complex with CMP | 分子名称: | CYTIDINE-5'-MONOPHOSPHATE, Protein argonaute 1 | 著者 | Frank, F, Hauver, J, Sonenberg, N, Nagar, B. | 登録日 | 2012-07-09 | 公開日 | 2012-07-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs. Embo J., 31, 2012
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5JV2
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![BU of 5jv2 by Molmil](/molmil-images/mine/5jv2) | Crystal structure of human FPPS in complex with an allosteric inhibitor MIT-01-055 | 分子名称: | CHLORIDE ION, Farnesyl pyrophosphate synthase, PHOSPHATE ION, ... | 著者 | Park, J, Magder, A, Tsakos, M, Tsantrizos, Y.S, Berghuis, A.M. | 登録日 | 2016-05-10 | 公開日 | 2017-03-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. J. Med. Chem., 60, 2017
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1I1P
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![BU of 1i1p by Molmil](/molmil-images/mine/1i1p) | REFINEMENT INCLUDING EXPERIMENTAL MAD PHASES ALLOWS AN EXHAUSTIVE STUDY OF ORDERED SOLVENT MOLECULES FOR A PLATINATED DECANUCLEOTIDE | 分子名称: | 5'-D(*CP*CP*TP*CP*GP*CP*TP*CP*TP*C)-3', 5'-D(*GP*AP*GP*AP*GP*CP*GP*AP*GP*G)-3', Cisplatin, ... | 著者 | Coste, F, Shepard, W, Zelwer, C. | 登録日 | 2001-02-02 | 公開日 | 2002-06-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Description of ordered solvent molecules in a platinated decanucleotide duplex refined at 1.6A resolution against experimental MAD phases. Acta Crystallogr.,Sect.D, 58, 2002
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3VTP
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7MJC
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7MJD
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![BU of 7mjd by Molmil](/molmil-images/mine/7mjd) | Crystal Structure Analysis of ALDH1B1 | 分子名称: | 8-(2-methoxyphenyl)-10-(4-phenylphenyl)-1$l^{4},8-diazabicyclo[5.3.0]deca-1(7),9-diene, Aldehyde dehydrogenase X, mitochondrial, ... | 著者 | Fernandez, D, Chen, J.K. | 登録日 | 2021-04-20 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Inhibitors targeted to aldehyde dehydrogenase Nat.Chem.Biol., 2022
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1O1E
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![BU of 1o1e by Molmil](/molmil-images/mine/1o1e) | MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE | 分子名称: | SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN, ... | 著者 | Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A. | 登録日 | 2002-11-19 | 公開日 | 2002-12-04 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (70 Å) | 主引用文献 | Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle J.Struct.Biol., 138, 2002
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5K1Z
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![BU of 5k1z by Molmil](/molmil-images/mine/5k1z) | Joint X-ray/neutron structure of MTAN complex with p-ClPh-Thio-DADMe-ImmA | 分子名称: | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(4-chlorophenyl)sulfanyl]methyl}pyrrolidin-3-ol, Aminodeoxyfutalosine nucleosidase | 著者 | Banco, M.T, Kovalevsky, A.Y, Ronning, D.R. | 登録日 | 2016-05-18 | 公開日 | 2016-11-16 | 最終更新日 | 2024-03-06 | 実験手法 | NEUTRON DIFFRACTION (2.6 Å), X-RAY DIFFRACTION | 主引用文献 | Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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6XMA
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![BU of 6xma by Molmil](/molmil-images/mine/6xma) | Crystal structure of iron-bound LSD4 from Sphingobium sp. strain SYK-6 | 分子名称: | Dioxygenase, FE (III) ION, SULFATE ION | 著者 | Kuatsjah, E, Chan, A.C, Katahira, R, Beckham, G.T, Murphy, M.E, Eltis, L.D. | 登録日 | 2020-06-29 | 公開日 | 2021-05-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6. J.Biol.Chem., 296, 2021
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