PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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6X71	Rev1 Mg2+-facilitated Intermediate complex with reactant dCTP and product dCMP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*CP*GP*CP*TP*AP*CP*CP*AP*CP*AP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*GP*C*(MG))-3'), ... 著者 Weaver, T.M, Freudenthal, B.D. 登録日 2020-05-29 公開日 2020-09-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Visualizing Rev1 catalyze protein-template DNA synthesis. Proc.Natl.Acad.Sci.USA, 117, 2020
7MHD	Thioesterase Domain of Human Fatty Acid Synthase (FASN-TE) binding a competitive inhibitor SBP-7635 分子名称: Fatty acid synthase, N,N-diethyl-4-{2-[(2-fluorophenyl)methyl]-1,3-thiazol-4-yl}benzene-1-sulfonamide 著者 Aleshin, A.E, Lambert, L, Liddington, R.C, Cosford, N. 登録日 2021-04-15 公開日 2022-04-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Thioesterase Domain of Human Fatty Acid Synthase (FASN-TE) binding a competitive inhibitor SBP-7635 To Be Published
3VGX	Structure of gp41 T21/Cp621-652 分子名称: ACETIC ACID, Envelope glycoprotein gp160, GLYCEROL 著者 Yao, X, Waltersperger, S, Wang, M, Cui, S. 登録日 2011-08-22 公開日 2012-04-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Discovery of critical residues for viral entry and inhibition through structural Insight of HIV-1 fusion inhibitor CP621-652. J.Biol.Chem., 287, 2012
4GID	Structure of beta-secretase complexed with inhibitor 分子名称: Beta-secretase 1, L-PROLINAMIDE, N-[(2S)-1-({(2S,3R)-3-hydroxy-1-[(2-methylpropyl)amino]-1-oxobutan-2-yl}amino)-3-phenylpropan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide 著者 Ghosh, A, Tang, J, Venkateswara, R.K, Yadav, N, Anderson, D, Gavande, N, Huang, X, Terzyan, S. 登録日 2012-08-08 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-based design of highly selective beta-secretase inhibitors: synthesis, biological evaluation, and protein-ligand X-ray crystal structure. J.Med.Chem., 55, 2012
7MHA	Crystal structure of R. sphaeroides Photosynthetic Reaction Center variant; W252V mutant 分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... 著者 Boxer, S.G, Mathews, I.I, Weaver, J.B. 登録日 2021-04-14 公開日 2022-04-27 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Photosynthetic reaction center variants made via genetic code expansion indicate tyrosine at M210 tunes the mechanism for primary electron transfer Thesis Ph.D. Stanford University, 2022
7MN0	N74D mutant of the HIV-1 capsid protein 分子名称: IODIDE ION, capsid protein 著者 Gres, A.T, Kirby, K.A, Sarafianos, S.G. 登録日 2021-04-30 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 TRIM5alpha Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection. Viruses, 14, 2022
7MKV	Engineered PLP-dependent decarboxylative aldolase from Aspergillus flavus, UstD2.0, bound as the internal aldimine 分子名称: Cysteine desulfurase-like protein ustD 著者 Ellis, J.M, Buller, A.R, Bingman, C.A. 登録日 2021-04-27 公開日 2022-05-04 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Biocatalytic synthesis of non-standard amino acids by a decarboxylative aldol reaction Nat Catal, 5, 2022
7MKC	N74D mutant of the HIV-1 capsid protein in complex with PF-3450074 (PF74) 分子名称: IODIDE ION, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE, capsid protein 著者 Kirby, K.A, Sarafianos, S.G. 登録日 2021-04-23 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 TRIM5alpha Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection. Viruses, 14, 2022
7MMQ	Crystal Structure of the Class Ie Ribonucleotide Reductase Beta-NrdI complex from Aerococcus urinae in Reduced Hydroquinone Form 分子名称: FLAVIN MONONUCLEOTIDE, GLYCEROL, Protein NrdI, ... 著者 Palowitch, G.M, Boal, A.K. 登録日 2021-04-30 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Ribonucleotide Reductase To be published
5KHZ	PSEUDO T4 LYSOZYME 分子名称: 2-HYDROXYETHYL DISULFIDE, Endolysin 著者 Scholfield, M.R. 登録日 2016-06-16 公開日 2017-04-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Structure-Energy Relationships of Halogen Bonds in Proteins. Biochemistry, 56, 2017
7MP4	Crystal structure of Epiphyas postvittana antennal carboxylesterase 24 分子名称: Carboxylesterase-24, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Hamiaux, C, Carraher, C. 登録日 2021-05-04 公開日 2022-05-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Structure of an antennally-expressed carboxylesterase suggests lepidopteran odorant degrading enzymes are broadly tuned Curr Res Insect Sci, 3, 2023
7MQP	E. coli dihydrofolate reductase complexed with 4'-chloro-3'-(4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl)-[1,1'-biphenyl]-4-carboxamide (UCP1228) 分子名称: 3'-[(2S)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-4'-methyl[1,1'-biphenyl]-4-carboxamide, Dihydrofolate reductase, SULFATE ION 著者 Lombardo, M.N, Wright, D.L. 登録日 2021-05-06 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens. Commun Biol, 5, 2022
7MRI	Crystal structure of N63T yeast iso-1-cytochrome c 分子名称: Cytochrome c isoform 1, HEME C 著者 Lei, H, Bowler, B.E, Evenson, G.E. 登録日 2021-05-07 公開日 2022-05-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Effect on intrinsic peroxidase activity of substituting coevolved residues from Omega-loop C of human cytochrome c into yeast iso-1-cytochrome c. J.Inorg.Biochem., 232, 2022
5K0W	Crystal structure of the metallo-beta-lactamase GOB-18 from Elizabethkingia meningoseptica 分子名称: CHLORIDE ION, Class B carbapenemase GOB-18, GLYCEROL, ... 著者 Buschiazzo, A, Larrieux, N, Vila, A.J, Lisa, M.N, Moran-Barrio, J. 登録日 2016-05-17 公開日 2016-08-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Crystal Structure of the Metallo-beta-Lactamase GOB in the Periplasmic Dizinc Form Reveals an Unusual Metal Site. Antimicrob.Agents Chemother., 60, 2016
7MW8	Crystal Structure Analysis of Xac Nucleotide Pyrophosphatase/Phosphodiesterase 分子名称: Phosphodiesterase-nucleotide pyrophosphatase, ZINC ION, pApG 著者 Fernandez, D, Li, L, Brown, J.A. 登録日 2021-05-15 公開日 2022-05-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 ENPP1's regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling. Proc.Natl.Acad.Sci.USA, 119, 2022
4G0M	Crystal structure of Arabidopsis thaliana AGO2 MID domain 分子名称: Protein argonaute 2, SULFATE ION 著者 Frank, F, Hauver, J, Sonenberg, N, Nagar, B. 登録日 2012-07-09 公開日 2012-07-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.306 Å) 主引用文献 Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs. Embo J., 31, 2012
4G0Q	Crystal structure of Arabidopsis thaliana AGO1 MID domain in complex with CMP 分子名称: CYTIDINE-5'-MONOPHOSPHATE, Protein argonaute 1 著者 Frank, F, Hauver, J, Sonenberg, N, Nagar, B. 登録日 2012-07-09 公開日 2012-07-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs. Embo J., 31, 2012
5JV2	Crystal structure of human FPPS in complex with an allosteric inhibitor MIT-01-055 分子名称: CHLORIDE ION, Farnesyl pyrophosphate synthase, PHOSPHATE ION, ... 著者 Park, J, Magder, A, Tsakos, M, Tsantrizos, Y.S, Berghuis, A.M. 登録日 2016-05-10 公開日 2017-03-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. J. Med. Chem., 60, 2017
1I1P	REFINEMENT INCLUDING EXPERIMENTAL MAD PHASES ALLOWS AN EXHAUSTIVE STUDY OF ORDERED SOLVENT MOLECULES FOR A PLATINATED DECANUCLEOTIDE 分子名称: 5'-D(*CP*CP*TP*CP*GP*CP*TP*CP*TP*C)-3', 5'-D(*GP*AP*GP*AP*GP*CP*GP*AP*GP*G)-3', Cisplatin, ... 著者 Coste, F, Shepard, W, Zelwer, C. 登録日 2001-02-02 公開日 2002-06-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Description of ordered solvent molecules in a platinated decanucleotide duplex refined at 1.6A resolution against experimental MAD phases. Acta Crystallogr.,Sect.D, 58, 2002
3VTP	HIV fusion inhibitor MT-C34 分子名称: Transmembrane protein gp41 著者 Yao, X, Waltersperger, S, Wang, M, Cui, S. 登録日 2012-06-02 公開日 2012-08-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The M-T hook structure is critical for design of HIV-1 fusion inhibitors. J.Biol.Chem., 287, 2012
7MJC	Crystal Structure Analysis of ALDH1B1 分子名称: Aldehyde dehydrogenase X, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Fernandez, D, Chen, J.K. 登録日 2021-04-20 公開日 2022-06-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Inhibitors targeted to aldehyde dehydrogenase Nat.Chem.Biol., 2022
7MJD	Crystal Structure Analysis of ALDH1B1 分子名称: 8-(2-methoxyphenyl)-10-(4-phenylphenyl)-1$l^{4},8-diazabicyclo[5.3.0]deca-1(7),9-diene, Aldehyde dehydrogenase X, mitochondrial, ... 著者 Fernandez, D, Chen, J.K. 登録日 2021-04-20 公開日 2022-06-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Inhibitors targeted to aldehyde dehydrogenase Nat.Chem.Biol., 2022
1O1E	MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 分子名称: SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN, ... 著者 Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A. 登録日 2002-11-19 公開日 2002-12-04 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (70 Å) 主引用文献 Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle J.Struct.Biol., 138, 2002
5K1Z	Joint X-ray/neutron structure of MTAN complex with p-ClPh-Thio-DADMe-ImmA 分子名称: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(4-chlorophenyl)sulfanyl]methyl}pyrrolidin-3-ol, Aminodeoxyfutalosine nucleosidase 著者 Banco, M.T, Kovalevsky, A.Y, Ronning, D.R. 登録日 2016-05-18 公開日 2016-11-16 最終更新日 2024-03-06 実験手法 NEUTRON DIFFRACTION (2.6 Å), X-RAY DIFFRACTION 主引用文献 Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
6XMA	Crystal structure of iron-bound LSD4 from Sphingobium sp. strain SYK-6 分子名称: Dioxygenase, FE (III) ION, SULFATE ION 著者 Kuatsjah, E, Chan, A.C, Katahira, R, Beckham, G.T, Murphy, M.E, Eltis, L.D. 登録日 2020-06-29 公開日 2021-05-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6. J.Biol.Chem., 296, 2021

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