5K0W

Crystal structure of the metallo-beta-lactamase GOB-18 from Elizabethkingia meningoseptica

Summary for 5K0W

• Entry DOI: 10.2210/pdb5k0w/pdb
• Descriptor: Class B carbapenemase GOB-18, ZINC ION, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: metallo-beta-lactamase, b3 lactamase, zinc hydrolase, hydrolysis of beta-lactam antibiotics, hydrolase
• Biological source: Elizabethkingia meningoseptica
• Total number of polymer chains: 2
• Total formula weight: 67373.62

Authors

Buschiazzo, A.,Larrieux, N.,Vila, A.J.,Lisa, M.N.,Moran-Barrio, J. (deposition date: 2016-05-17, release date: 2016-08-03, Last modification date: 2023-09-27)

• Primary citation: Moran-Barrio, J.,Lisa, M.N.,Larrieux, N.,Drusin, S.I.,Viale, A.M.,Moreno, D.M.,Buschiazzo, A.,Vila, A.J.; Crystal Structure of the Metallo-beta-Lactamase GOB in the Periplasmic Dizinc Form Reveals an Unusual Metal Site.; Antimicrob.Agents Chemother., 60:6013-6022, 2016; PubMed: 27458232; DOI: 10.1128/AAC.01067-16

Experimental method

X-RAY DIFFRACTION (2.61 Å)