7MHD

Thioesterase Domain of Human Fatty Acid Synthase (FASN-TE) binding a competitive inhibitor SBP-7635

Summary for 7MHD

• Entry DOI: 10.2210/pdb7mhd/pdb
• Descriptor: Fatty acid synthase, N,N-diethyl-4-{2-[(2-fluorophenyl)methyl]-1,3-thiazol-4-yl}benzene-1-sulfonamide (3 entities in total)
• Functional Keywords: thioesterase domain, fatty acid synthase, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 32929.19

Authors

Aleshin, A.E.,Lambert, L.,Liddington, R.C.,Cosford, N. (deposition date: 2021-04-15, release date: 2022-04-20, Last modification date: 2023-10-18)

• Primary citation: Aleshin, A.E.,Lambert, L.,Liddington, R.C.,Cosford, N.; Thioesterase Domain of Human Fatty Acid Synthase (FASN-TE) binding a competitive inhibitor SBP-7635; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.03 Å)