7MHD
Thioesterase Domain of Human Fatty Acid Synthase (FASN-TE) binding a competitive inhibitor SBP-7635
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Fatty acid synthase | polymer | 298 | 32524.7 | 1 | UniProt (P49327) Pfam (PF00975) | Homo sapiens (Human) | Type I fatty acid synthase |
| 2 | B (A) | N,N-diethyl-4-{2-[(2-fluorophenyl)methyl]-1,3-thiazol-4-yl}benzene-1-sulfonamide | non-polymer | 404.5 | 1 | Chemie (ZEP) | |||
| 3 | C (A) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A: 215 - 503 (UniProt: P49327)
| PDB | External Database | Details |
|---|---|---|
| Gly 207 | - | expression tag |
| Ser 208 | - | expression tag |
| Gly 209 | - | expression tag |
| Gly 210 | - | expression tag |
| Gly 211 | - | expression tag |
| Gly 212 | - | expression tag |
| Gly 213 | - | expression tag |
| Ser 214 | - | expression tag |
| His 504 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32524.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 404.5 | |
| All* | Total formula weight | 32929.2 |
