5K1Z

Joint X-ray/neutron structure of MTAN complex with p-ClPh-Thio-DADMe-ImmA

Summary for 5K1Z

• Entry DOI: 10.2210/pdb5k1z/pdb
• Related: 5JPC
• Descriptor: Aminodeoxyfutalosine nucleosidase, (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(4-chlorophenyl)sulfanyl]methyl}pyrrolidin-3-ol (3 entities in total)
• Functional Keywords: neutron, nucleosidase, joint neutron and x-ray, helicobacter pylori, hydrolase
• Biological source: Helicobacter pylori
• Total number of polymer chains: 1
• Total formula weight: 25308.60

Authors

Banco, M.T.,Kovalevsky, A.Y.,Ronning, D.R. (deposition date: 2016-05-18, release date: 2016-11-16, Last modification date: 2024-03-06)

• Primary citation: Banco, M.T.,Mishra, V.,Ostermann, A.,Schrader, T.E.,Evans, G.B.,Kovalevsky, A.,Ronning, D.R.; Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states.; Proc. Natl. Acad. Sci. U.S.A., 113:13756-13761, 2016; PubMed: 27856757; DOI: 10.1073/pnas.1609718113

Experimental method

NEUTRON DIFFRACTION (2.6 Å)
X-RAY DIFFRACTION (2.25 Å)