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2B3U
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Human Spermine spermidine acetyltransferase K26R mutant
分子名称: Diamine acetyltransferase 1, SULFATE ION
著者Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2005-09-21
公開日2006-01-17
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target.
Proc.Natl.Acad.Sci.USA, 103, 2006
8SG4
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E1435Q Ycf1 mutant in dephosphorylated state
分子名称: Metal resistance protein YCF1
著者Khandelwal, N.K, Tomasiak, T.M.
登録日2023-04-11
公開日2024-03-06
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structural basis for autoinhibition by the dephosphorylated regulatory domain of Ycf1.
Nat Commun, 15, 2024
5VOY
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Yeast V-ATPase in complex with Legionella pneumophila effector SidK (rotational state 2)
分子名称: V-type proton ATPase catalytic subunit A,V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
著者Zhao, J.
登録日2017-05-03
公開日2017-06-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
PLoS Pathog., 13, 2017
5L92
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The 2.1 A crystal structure of CYP109E1 from Bacillus megaterium in complex with corticosterone
分子名称: CORTICOSTERONE, Cytochrome P450, MALONIC ACID, ...
著者Jozwik, I.K, Thunnissen, A.M.W.H.
登録日2016-06-09
公開日2016-10-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium.
Febs J., 283, 2016
5L91
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The 2.2 A crystal structure of CYP109E1 from Bacillus megaterium bound with four corticosterone molecules
分子名称: CORTICOSTERONE, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
著者Jozwik, I.K, Thunnissen, A.M.W.H.
登録日2016-06-09
公開日2016-10-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium.
Febs J., 283, 2016
5VOZ
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Yeast V-ATPase in complex with Legionella pneumophila effector SidK (rotational state 3)
分子名称: Uncharacterized protein, V-type proton ATPase catalytic subunit A,V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, ...
著者Zhao, J.
登録日2017-05-03
公開日2017-06-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
PLoS Pathog., 13, 2017
2CDN
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BU of 2cdn by Molmil
Crystal structure of Mycobacterium tuberculosis adenylate kinase complexed with two molecules of ADP and Mg
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENYLATE KINASE, MAGNESIUM ION
著者Bellinzoni, M, Haouz, A, Grana, M, Munier-Lehmann, H, Alzari, P.M.
登録日2006-01-25
公開日2006-05-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Crystal Structure of Mycobacterium Tuberculosis Adenylate Kinase in Complex with Two Molecules of Adp and Mg2+ Supports an Associative Mechanism for Phosphoryl Transfer.
Protein Sci., 15, 2006
6O7V
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Saccharomyces cerevisiae V-ATPase Stv1-V1VO State 1
分子名称: Putative protein YPR170W-B, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
著者Vasanthakumar, T, Bueler, S.A, Wu, D, Beilsten-Edmands, V, Robinson, C.V, Rubinstein, J.L.
登録日2019-03-08
公開日2019-04-03
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Structural comparison of the vacuolar and Golgi V-ATPases fromSaccharomyces cerevisiae.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
4PJO
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BU of 4pjo by Molmil
Minimal U1 snRNP
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ETHANOL, ...
著者Kondo, Y, Oubridge, C, van Roon, A.M, Nagai, K.
登録日2014-05-12
公開日2014-12-31
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
Elife, 4, 2015
5L90
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The crystal structure of substrate-free CYP109E1 from Bacillus megaterium at 2.55 Angstrom resolution
分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
著者Jozwik, I.K, Thunnissen, A.M.W.H.
登録日2016-06-09
公開日2016-10-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium.
Febs J., 283, 2016
4H6Y
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Crystal structure of the DH-PH-PH domain of FARP1
分子名称: FERM, RhoGEF and pleckstrin domain-containing protein 1
著者He, X, Zhang, X.
登録日2012-09-19
公開日2013-03-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.09 Å)
主引用文献Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2.
Structure, 21, 2013
8GK8
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BU of 8gk8 by Molmil
R21A Staphylococcus aureus pyruvate carboxylase
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, COENZYME A, ...
著者Laseke, A.J, St.Maurice, M.
登録日2023-03-17
公開日2023-08-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Allosteric Site at the Biotin Carboxylase Dimer Interface Mediates Activation and Inhibition in Staphylococcus aureus Pyruvate Carboxylase.
Biochemistry, 62, 2023
8FL3
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Human nuclear pre-60S ribosomal subunit (State I2)
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Vanden Broeck, A, Klinge, S.
登録日2022-12-21
公開日2023-07-12
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献Principles of human pre-60 S biogenesis.
Science, 381, 2023
8FL2
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Human nuclear pre-60S ribosomal subunit (State I1)
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Vanden Broeck, A, Klinge, S.
登録日2022-12-21
公開日2023-07-12
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.67 Å)
主引用文献Principles of human pre-60 S biogenesis.
Science, 381, 2023
4ZH2
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BU of 4zh2 by Molmil
Crystal structure of Escherichia coli RNA polymerase in complex with CBR703
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Feng, Y, Ebright, R.H.
登録日2015-04-24
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.204 Å)
主引用文献Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.
Structure, 23, 2015
6VCB
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BU of 6vcb by Molmil
Cryo-EM structure of the Glucagon-like peptide-1 receptor in complex with G protein, GLP-1 peptide and a positive allosteric modulator
分子名称: 1-[(1R)-1-(2,6-dichloro-3-methoxyphenyl)ethyl]-6-{2-[(2R)-piperidin-2-yl]phenyl}-1H-benzimidazole, Glucagon-like peptide 1, Glucagon-like peptide 1 receptor, ...
著者Sun, B, Feng, D, Bueno, A, Kobilka, B, Sloop, K.
登録日2019-12-20
公開日2020-07-22
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into probe-dependent positive allosterism of the GLP-1 receptor.
Nat.Chem.Biol., 16, 2020
1LC6
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Solution Structure of the U6 Intramolecular Stem-loop RNA
分子名称: U6 Intramolecular Stem-loop RNA
著者Huppler, A, Nikstad, L.J, Allmann, A.M, Brow, D.A, Butcher, S.E.
登録日2002-04-05
公開日2002-05-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Metal binding and base ionization in the U6 RNA intramolecular stem-loop structure.
Nat.Struct.Biol., 9, 2002
6O7W
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BU of 6o7w by Molmil
Saccharomyces cerevisiae V-ATPase Stv1-V1VO State 2
分子名称: Putative protein YPR170W-B, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
著者Vasanthakumar, T, Bueler, S.A, Wu, D, Beilsten-Edmands, V, Robinson, C.V, Rubinstein, J.L.
登録日2019-03-08
公開日2019-04-03
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Structural comparison of the vacuolar and Golgi V-ATPases fromSaccharomyces cerevisiae.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6TGC
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BU of 6tgc by Molmil
CryoEM structure of the ternary DOCK2-ELMO1-RAC1 complex.
分子名称: Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1
著者Chang, L, Yang, J, Chang, J.H, Zhang, Z, Boland, A, McLaughlin, S.H, Abu-Thuraia, A, Killoran, R.C, Smith, M.J, Cote, J.F, Barford, D.
登録日2019-11-15
公開日2020-07-29
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state.
Nat Commun, 11, 2020
6TVG
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Human CD73 (ecto 5'-nucleotidase) in complex with AMPCP in the open state
分子名称: 5'-nucleotidase, ecto (CD73), isoform CRA_a, ...
著者Scaletti, E, Strater, N.
登録日2020-01-09
公開日2020-02-26
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献2-Substituted alpha , beta-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.
J.Med.Chem., 63, 2020
1LB5
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TRAF6-RANK Complex
分子名称: TNF receptor-associated factor 6, receptor activator of nuclear factor-kappa B
著者Ye, H, Arron, J.R, Lamothe, B, Cirilli, M, Kobayashi, T, Shevde, N.K, Segal, D, Dzivenu, O, Vologodskaia, M, Yim, M, Du, K, Singh, S, Pike, J.W, Darnay, B.G, Choi, Y, Wu, H.
登録日2002-04-02
公開日2002-07-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Distinct molecular mechanism for initiating TRAF6 signalling.
Nature, 418, 2002
1LB4
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TRAF6 apo structure
分子名称: TNF receptor-associated factor 6
著者Ye, H, Arron, J.R, Lamothe, B, Cirilli, M, Kobayashi, T, Shevde, N.K, Segal, D, Dzivenu, O, Vologodskaia, M, Yim, M, Du, K, Singh, S, Pike, J.W, Darnay, B.G, Choi, Y, Wu, H.
登録日2002-04-02
公開日2002-07-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Distinct molecular mechanism for initiating TRAF6 signalling.
Nature, 418, 2002
7Y7A
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In situ double-PBS-PSII-PSI-LHCs megacomplex from Porphyridium purpureum.
分子名称: (1R,2S)-4-{(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl}-2,5,5-trimethylcyclohex-3-en-1-ol, (2S)-2,3-dihydroxypropyl octadecanoate, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ...
著者You, X, Zhang, X, Cheng, J, Xiao, Y.N, Sun, S, Sui, S.F.
登録日2022-06-22
公開日2023-02-08
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献In situ structure of the red algal phycobilisome-PSII-PSI-LHC megacomplex.
Nature, 616, 2023
8Q74
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Copper-transporting ATPase HMA4 in E1 state with Cu
分子名称: COPPER (II) ION, Copper-transporting ATPase HMA4
著者Guo, Z, Gourdon, P, Wang, K.
登録日2023-08-15
公開日2024-06-26
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Diverse roles of the metal binding domains and transport mechanism of copper transporting P-type ATPases.
Nat Commun, 15, 2024
5B6N
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Crystal structures of human peroxiredoxin 6 in sulfinic acid state
分子名称: Peroxiredoxin-6
著者Kim, K.H, Lee, W.T, Kim, E.E.
登録日2016-05-30
公開日2016-07-13
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.895 Å)
主引用文献Crystal structures of human peroxiredoxin 6 in different oxidation states
Biochem.Biophys.Res.Commun., 477, 2016

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