8GK8
R21A Staphylococcus aureus pyruvate carboxylase
Summary for 8GK8
| Entry DOI | 10.2210/pdb8gk8/pdb |
| Descriptor | Pyruvate carboxylase, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, ... (6 entities in total) |
| Functional Keywords | biotin dependent ligase, ligase |
| Biological source | Staphylococcus aureus |
| Total number of polymer chains | 4 |
| Total formula weight | 517603.94 |
| Authors | Laseke, A.J.,St.Maurice, M. (deposition date: 2023-03-17, release date: 2023-08-30, Last modification date: 2024-03-13) |
| Primary citation | Laseke, A.J.,Boram, T.J.,Schneider, N.O.,Lohman, J.R.,St Maurice, M. Allosteric Site at the Biotin Carboxylase Dimer Interface Mediates Activation and Inhibition in Staphylococcus aureus Pyruvate Carboxylase. Biochemistry, 62:2632-2644, 2023 Cited by PubMed: 37603581DOI: 10.1021/acs.biochem.3c00280 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.68 Å) |
Structure validation
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